PD 102807 | Tocris Bioscience 1671/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PD 102807

catalog :

1671/10

quantity :

10 mg (also 50 mg)

price :

300 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Trivedi G, Inoue D, Chen C, Bitner L, Chung Y, Taylor J, et al. Muscarinic acetylcholine receptor regulates self-renewal of early erythroid progenitors. Sci Transl Med. 2019;11: pubmed publisher
Zhu H, Yan H, Tang N, Li X, Pang P, Li H, et al. Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses. Nat Commun. 2017;8:1676 pubmed publisher
Thomson S, Seo S, Barnes S, Louros S, Muscas M, Dando O, et al. Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome. Neuron. 2017;95:550-563.e5 pubmed publisher
Solanki P, Cuprian Beltechi A, Cunnane T. Cholinergic innervation of the guinea-pig isolated vas deferens. Naunyn Schmiedebergs Arch Pharmacol. 2007;376:265-74 pubmed

product information

brand :

Tocris

catalog number base :

1671

SKU :

1671/10

product name :

PD 102807

units size :

10 mg (also 50 mg)

description :

Selective M4 antagonist

target :

mAChR M4 Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

392.45

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

review stars :

details of functionality :

PD 102807 is a selective M4 muscarinic receptor antagonist. IC50 values are 91, 6559, 3441, 950 and 7412 nM for human M4, M1, M2, M3, and M5 receptors respectively. Promotes self-renewal of erythroid progenitors.

top caption :

Selective M4 antagonist

extended description :

Selective M4 antagonist

chemical name text :

3,6a,11,14-Tetrahydro-9-methoxy-2-methyl-(12H)-isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid, ethyl ester

formula :

C23H24N2O4

formula text :

C23H24N2O4

cas num :

23062-91-1

USD :

300 USD

product details :

Selective M4 antagonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage