PD 102807 | Tocris Bioscience 1671/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PD 102807

catalog :

1671/10

quantity :

10 mg (also 50 mg)

price :

300 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Trivedi G, Inoue D, Chen C, Bitner L, Chung Y, Taylor J, et al. Muscarinic acetylcholine receptor regulates self-renewal of early erythroid progenitors. Sci Transl Med. 2019;11: pubmed publisher
Zhu H, Yan H, Tang N, Li X, Pang P, Li H, et al. Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses. Nat Commun. 2017;8:1676 pubmed publisher
Thomson S, Seo S, Barnes S, Louros S, Muscas M, Dando O, et al. Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome. Neuron. 2017;95:550-563.e5 pubmed publisher
Solanki P, Cuprian Beltechi A, Cunnane T. Cholinergic innervation of the guinea-pig isolated vas deferens. Naunyn Schmiedebergs Arch Pharmacol. 2007;376:265-74 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1671

SKU :

1671/10

product name :

PD 102807

description :

Selective M4 antagonist

target :

mAChR M4 Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

392.45

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PD 102807 is a selective M4 muscarinic receptor antagonist. IC50 values are 91, 6559, 3441, 950 and 7412 nM for human M4, M1, M2, M3, and M5 receptors respectively. Promotes self-renewal of erythroid progenitors.

product keywords :

Selective M4 antagonists antagonism Muscarinic Receptors Acetylcholine ACh PD102807 expansion self-renewal hematopoietic progenitors burst-forming units erythroid BFU-E mAChR4 M4 Receptors Stem Cell Proliferation 1671,

extended description :

Selective M4 antagonist

chemical name text :

3,6a,11,14-Tetrahydro-9-methoxy-2-methyl-(12H)-isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid, ethyl ester

formula :

C23H24N2O4

formula text :

C23H24N2O4

cas num :

23062-91-1

USD :

287

USD 2025 :

300 USD

product details :

Selective M4 antagonist

more info or order :

Tocris Bioscience product webpage