product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
GR 73632
catalog :
1669/1
quantity :
1 mg
price :
469 USD
more info or order :
citations: 5
Reference
Sheahan T, Warwick C, Fanien L, Ross S. The Neurokinin-1 Receptor is Expressed with Gastrin-Releasing Peptide Receptor in Spinal Interneurons and Modulates Itch. J Neurosci. 2020;40:8816-8830 pubmed publisher
León S, Barroso A, Vázquez M, García Galiano D, Manfredi Lozano M, Ruiz Pino F, et al. Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity. Sci Rep. 2016;6:19206 pubmed publisher
Ruiz Pino F, Garcia Galiano D, Manfredi Lozano M, Leon S, Sánchez Garrido M, Roa J, et al. Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats. Endocrinology. 2015;156:576-88 pubmed publisher
Navarro V, Bosch M, Leon S, Simavli S, True C, Pinilla L, et al. The integrated hypothalamic tachykinin-kisspeptin system as a central coordinator for reproduction. Endocrinology. 2015;156:627-37 pubmed publisher
Liu B, ESCALERA J, Balakrishna S, Fan L, Caceres A, Robinson E, et al. TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis. FASEB J. 2013;27:3549-63 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1669
SKU :
1669/1
product name :
GR 73632
description :
Potent and selective NK1 agonist
target :
NK1 Receptor Agonists
unit size :
1 mg
category :
Peptides
purity :
95%
storage :
Store at -20°C
observed molecular weight :
766.01
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
GR 73632 is a potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). Active in vivo . Intrathecal administration of GR 73632 in mice increases itch behavior.
product keywords :
Potent selective NK1 agonists Tachykinin Receptors Neurokinin GR73632 GlaxoSmithKline GSK NK1 Receptor 1669, Neurokinin NK1
extended description :
Potent and selective NK1 agonist
formula :
C40H59N7O6S
formula text :
C40H59N7O6S
cas num :
133156-06-6
USD :
450
USD 2025 :
469 USD
product details :
Potent and selective NK1 agonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK