GR 125487 sulfamate | Tocris Bioscience 1658 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GR 125487 sulfamate

catalog :

1658

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Orr A, Hsiao E, Wang M, Ho K, Kim D, Wang X, et al. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nat Neurosci. 2015;18:423-34 pubmed publisher
Warner Schmidt J, Flajolet M, Maller A, Chen E, Qi H, Svenningsson P, et al. Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation. J Neurosci. 2009;29:1937-46 pubmed publisher

product information

brand :

Tocris

master code :

1658

SKU :

1658/10

product name :

GR 125487 sulfamate

description :

Potent and selective 5-HT4 antagonist; active in vivo

target :

5-HT4 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

524.58

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective 5-HT4 receptor antagonist (Ki = 0.19 nM for porcine 5-HT4). Centrally active following systemic administration in vivo .

catalog number base :

1658

product keywords :

Potent selective 5-HT4 antagonists Serotonin Receptors 5-Hydroxytryptamine GR125487 sulfamate GlaxoSmithKline GSK 5-HT4 Receptors 1658,

extended description :

Potent and selective 5-HT4 antagonist; active in vivo

chemical name text :

5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate sulfamate

formula :

C 19 H 26 FN 3 O 5 S.H 2 NSO 3 H

formula text :

C19H26FN3O5S.H2NSO3H

cas num :

859502-43-5

2020 USD :

214

2021 USD :

223 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage