Lonidamine | Tocris Bioscience 1646/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Lonidamine

catalog :

1646/10

quantity :

10 mg (also 50 mg)

price :

121 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Panina S, Baran N, Brasil da Costa F, Konopleva M, Kirienko N. A mechanism for increased sensitivity of acute myeloid leukemia to mitotoxic drugs. Cell Death Dis. 2019;10:617 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1646

SKU :

1646/10

product name :

Lonidamine

description :

Mitochondrial hexokinase inhibitor

target :

Mitochondrial Hexokinase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

321.16

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Lonidamine is an anticancer and antispermatogenic agent in vitro and in vivo . Inhibits cellular energy metabolism in some cells via inhibition of mitochondrial hexokinase. Also blocks CFTR Cl- channels in vitro .

product keywords :

Mitochondrial hexokinase inhibitors inhibits CFTR Cl- chloride channels blockers Carbohydrate Metabolism Kinases AF1890 AF 1890 Hexokinases CFTR 1646,

extended description :

Mitochondrial hexokinase inhibitor

chemical name text :

1-[(2,4-Dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid

formula :

C15H10Cl2N2O2

formula text :

C15H10Cl2N2O2

cas num :

50264-69-2

USD :

119

USD 2025 :

121 USD

product details :

Mitochondrial hexokinase inhibitor

alt names :

AF 1890

more info or order :

Tocris Bioscience product webpage