Mesulergine hydrochloride | Tocris Bioscience 1644/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Mesulergine hydrochloride

catalog :

1644/10

quantity :

10 mg (also 50 mg)

price :

246 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Moutkine I, Quentin E, Guiard B, Maroteaux L, Doly S. Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT2C protomers. J Biol Chem. 2017;292:6352-6368 pubmed publisher
Chan J, Agbedanu P, Grab T, Zamanian M, Dosa P, Day T, et al. Ergot Alkaloids (Re)generate New Leads as Antiparasitics. PLoS Negl Trop Dis. 2015;9:e0004063 pubmed publisher

product information

brand :

Tocris

master code :

1644

SKU :

1644/10

product name :

Mesulergine hydrochloride

description :

5-HT2A and 5-HT2C antagonist; also D2-like partial agonist

target :

5-HT2A Receptor Antagonists

category :

Small Molecules

unit sizes :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

398.95

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Mesulergine hydrochloride is a 5-HT2A and 2C receptor antagonist (pA2 values are 9.1 for each receptor) and D2-like dopamine receptor partial agonist (Ki = 8 nM). Displays antiprolactin and antiparkinsonian effects in vivo .

extended description :

5-HT2A and 5-HT2C antagonist; also D2-like partial agonist

chemical name text :

N -[(8- 1,6-dimethylergolin-8-yl]-N,N-dimethylsulfamide hydrochloride

formula :

C 18 H 26 N 4 O 2 S.HCl

formula text :

C18H26N4O2S.HCl

cas num :

72786-12-0

USD :

246 USD

product details :

5-HT2A and 5-HT2C antagonist; also D2-like partial agonist

alt names :

CU-32-085

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage