Calphostin C | Tocris Bioscience 1626/100 product information

product summary

request information :

company name :

Tocris Bioscience

product type :

chemical

product name :

Calphostin C

catalog :

1626/100

quantity :

100µg

price :

175 USD

more info or order :

Tocris Bioscience product webpage

product information

CHEMISTRY :

O=C1C(OC)=C(CC(C)OC(C6=CC=CC=C6)=O)C3=C5C4=C(C(OC)=CC(O)=C4C(C(OC)=C5CC(C)OC(OC7=CC=C(O)C=C7)=O)=O)C2=C(OC)C=C(O)C1=C23

Cat Number :

1626/100

Product Name :

Calphostin C

Cas Number :

[121263-19-2]

Unit Size :

100µg

Size :

100

Unit :

µg

USD :

175 USD

Primary Category :

Enzymes

Secondary Category :

Kinases

Tertiary Category :

Protein Kinase C

Primary Action :

Potent, selective and photo-dependent PKC inhibitor

Biological Description :

Potent, selective and photo-dependent inhibitor of protein kinase C that targets the regulatory domain (IC50 = 50 nM). Displays > 1000-fold selectivity over other protein kinases such as cAMP-dependent protein kinase and tyrosine-specific protein kinase. Inhibits cell proliferation of malignant glioma cells in light-treated conditions in vitro (IC50 ~ 40 - 60 nM). Also an antagonist of the Tcf/β-catenin complex.

Formula :

C44H38O14

Molwt :

790.76

Synonyms :

UCN 1028C PKF 115584

more info or order :

Tocris Bioscience product webpage