DFB | Tocris Bioscience 1625 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DFB

catalog :

1625

quantity :

10 mg (also 50 mg)

price :

101 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Chen H, Liao P, Chan M. mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway. J Biomed Sci. 2011;18:19 pubmed publisher

product information

brand :

Tocris

master code :

1625

SKU :

1625/10

product name :

DFB

description :

Positive allosteric modulator of mGlu5 receptors

target :

Group I mGluR Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

244.24

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Novel allosteric potentiator of the metabotropic glutamate receptor mGlu5. Devoid of agonist activity itself, but potentiates (3 - 6-fold) the action of agonists at mGlu5 without any effect at other mGlu subtypes (EC50 for potentiation = 2 - 5.3 u M).

catalog number base :

1625

product keywords :

Allosteric potentiators mGlu5 mGluR5 Group I Receptors Glutamate Metabotropic PAM 3,3'-Difluorobenzaldazine Glutamate (Metabotropic) Group I Receptors 1625,

extended description :

Positive allosteric modulator of mGlu5 receptors

chemical name text :

[(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde

formula :

C 14 H 10 F 2 N 2

formula text :

C14H10F2N2

cas num :

15332-10-2

2020 USD :

2021 USD :

101 USD

alt names :

3,3 -Difluorobenzaldazine

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage