| Reference |
|---|
Schäfer S, Mansour A, Schlachetzki J, Pena M, Ghassemzadeh S, Mitchell L, et al. An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell. 2023;186:2111-2126.e20 pubmed publisher |
Surendran H, Soundararajan L, Reddy K V, Subramani J, Stoddard J, Reynaga R, et al. An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells. STAR Protoc. 2022;3:101803 pubmed publisher |
Rosebrock D, Arora S, Mutukula N, Volkman R, Gralinska E, Balaskas A, et al. Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells. Nat Cell Biol. 2022;24:981-995 pubmed publisher |
Kim T, Piao J, Koo S, Kriks S, Chung S, Betel D, et al. Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. Cell Stem Cell. 2021;28:343-355.e5 pubmed publisher |
Piao J, Zabierowski S, Dubose B, Hill E, Navare M, Claros N, et al. Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Cell Stem Cell. 2021;28:217-229.e7 pubmed publisher |
Yang L, Han Y, Nilsson Payant B, Gupta V, Wang P, Duan X, et al. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids. Cell Stem Cell. 2020;27:125-136.e7 pubmed publisher |
Gentsch G, Spruce T, Owens N, Smith J. Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. Nat Commun. 2019;10:4269 pubmed publisher |
Yoshimatsu S, Sone T, Nakajima M, Sato T, Okochi R, Ishikawa M, et al. A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology. PLoS ONE. 2019;14:e0221164 pubmed publisher |
Balbi C, Lodder K, Costa A, Moimas S, Moccia F, van Herwaarden T, et al. Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretome. Data Brief. 2019;25:104324 pubmed publisher |
Yin X, Xu J, Cho G, Kwon C, Dawson T, Dawson V. Neurons Derived from Human Induced Pluripotent Stem Cells Integrate into Rat Brain Circuits and Maintain Both Excitatory and Inhibitory Synaptic Activities. Eneuro. 2019;6: pubmed publisher |
Canfield S, Stebbins M, Faubion M, Gastfriend B, Palecek S, Shusta E. An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons. Fluids Barriers CNS. 2019;16:25 pubmed publisher |
Caron J, Pène V, Tolosa L, Villaret M, Luce E, Fourrier A, et al. Low-density lipoprotein receptor-deficient hepatocytes differentiated from induced pluripotent stem cells allow familial hypercholesterolemia modeling, CRISPR/Cas-mediated genetic correction, and productive hepatitis C virus infection. Stem Cell Res Ther. 2019;10:221 pubmed publisher |
Garcia V, Rushton D, Tom C, Allen N, Kemp P, Svendsen C, et al. Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support. Front Neurosci. 2019;13:669 pubmed publisher |
Gentsch G, Owens N, Smith J. The Spatiotemporal Control of Zygotic Genome Activation. iScience. 2019;16:485-498 pubmed publisher |
Nguyen L, Spitzhorn L, Adjaye J. Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells. Stem Cells Int. 2019;2019:3298432 pubmed publisher |
Xiang C, Du Y, Meng G, Soon Yi L, Sun S, Song N, et al. Long-term functional maintenance of primary human hepatocytes in vitro. Science. 2019;364:399-402 pubmed publisher |
Easterbrook J, Rybtsov S, Gordon Keylock S, Ivanovs A, Taoudi S, Anderson R, et al. Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo. Stem Cell Reports. 2019;12:1056-1068 pubmed publisher |
Baror R, Neumann B, SEGEL M, Chalut K, Fancy S, Schafer D, et al. Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors. Glia. 2019;67:1374-1384 pubmed publisher |
Colunga T, Hayworth M, Kreß S, Reynolds D, Chen L, Nazor K, et al. Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair. Cell Rep. 2019;26:2566-2579.e10 pubmed publisher |
Varghese D, Alawathugoda T, Ansari S. Fine Tuning of Hepatocyte Differentiation from Human Embryonic Stem Cells: Growth Factor vs. Small Molecule-Based Approaches. Stem Cells Int. 2019;2019:5968236 pubmed publisher |
Yin J, Zhang L, Ma N, Wang Y, Lee G, Hou X, et al. Chemical Conversion of Human Fetal Astrocytes into Neurons through Modulation of Multiple Signaling Pathways. Stem Cell Reports. 2019;12:488-501 pubmed publisher |
Bise T, de Preux Charles A, Jazwinska A. Ciliary neurotrophic factor stimulates cardioprotection and the proliferative activity in the adult zebrafish heart. NPJ Regen Med. 2019;4:2 pubmed publisher |
Frith T, Tsakiridis A. Efficient Generation of Trunk Neural Crest and Sympathetic Neurons from Human Pluripotent Stem Cells Via a Neuromesodermal Axial Progenitor Intermediate. Curr Protoc Stem Cell Biol. 2019;49:e81 pubmed publisher |
Haidar M, Asselbergh B, Adriaenssens E, de Winter V, Timmermans J, Auer Grumbach M, et al. Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies. Autophagy. 2019;15:1051-1068 pubmed publisher |
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher |
Paonessa F, Evans L, Solanki R, Larrieu D, Wray S, Hardy J, et al. Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia. Cell Rep. 2019;26:582-593.e5 pubmed publisher |
Aquino Martínez R, Monroe D, Ventura F. Calcium mimics the chemotactic effect of conditioned media and is an effective inducer of bone regeneration. PLoS ONE. 2019;14:e0210301 pubmed publisher |
Sharma N, Dev R, Belenchia A, Aroor A, Whaley Connell A, Pulakat L, et al. Deficiency of IL12p40 (Interleukin 12 p40) Promotes Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysm. Arterioscler Thromb Vasc Biol. 2019;39:212-223 pubmed publisher |
Yoon S, Elahi L, Pasca A, Marton R, Gordon A, Revah O, et al. Reliability of human cortical organoid generation. Nat Methods. 2019;16:75-78 pubmed publisher |
Lang C, Campbell K, Ryan B, Carling P, Attar M, Vowles J, et al. Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes. Cell Stem Cell. 2019;24:93-106.e6 pubmed publisher |
Subramanian A, Kanzaki L, Galloway J, Schilling T. Mechanical force regulates tendon extracellular matrix organization and tenocyte morphogenesis through TGFbeta signaling. elife. 2018;7: pubmed publisher |
Bayo Puxan N, Terrasso A, Creyssels S, Simão D, Begon Pescia C, Lavigne M, et al. Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons. Sci Rep. 2018;8:16644 pubmed publisher |
Serrano F, Bernard W, Granata A, Iyer D, Steventon B, Kim M, et al. A novel human pluripotent stem cell-derived neural crest model of Treacher Collins Syndrome shows defects in cell death and migration. Stem Cells Dev. 2018;: pubmed publisher |
Mehta S, Tom C, Wang Y, Bresee C, Rushton D, Mathkar P, et al. Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation. Cell Rep. 2018;25:1081-1096.e6 pubmed publisher |
Tebbenkamp A, Varela L, Choi J, Paredes M, Giani A, Song J, et al. The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development. Cell. 2018;175:1088-1104.e23 pubmed publisher |
Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch L, Eckert D, et al. A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. Nat Commun. 2018;9:4047 pubmed publisher |
Li X, Tao Y, Bradley R, Du Z, Tao Y, Kong L, et al. Fast Generation of Functional Subtype Astrocytes from Human Pluripotent Stem Cells. Stem Cell Reports. 2018;11:998-1008 pubmed publisher |
Molina M, Quirin M, Haillot E, de Crozé N, Range R, Rouel M, et al. MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo. PLoS Genet. 2018;14:e1007621 pubmed publisher |
Sloan S, Andersen J, Pasca A, Birey F, Paşca S. Generation and assembly of human brain region-specific three-dimensional cultures. Nat Protoc. 2018;13:2062-2085 pubmed publisher |
McCauley K, Hawkins F, Kotton D. Derivation of Epithelial-Only Airway Organoids from Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 2018;45:e51 pubmed publisher |
Magro Lopez E, Palmer C, Manso J, Liste I, Zambrano A. Effects of lung and airway epithelial maturation cocktail on the structure of lung bud organoids. Stem Cell Res Ther. 2018;9:186 pubmed publisher |
Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, et al. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell. 2018;23:123-131.e6 pubmed publisher |
Yang Q, Yan C, Gong Z. Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish. Sci Rep. 2018;8:8495 pubmed publisher |
Nehme R, Zuccaro E, Ghosh S, Li C, Sherwood J, Pietiläinen O, et al. Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Rep. 2018;23:2509-2523 pubmed publisher |
Medelnik J, Roensch K, Okawa S, del Sol A, Chara O, Mchedlishvili L, et al. Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells. Stem Cell Reports. 2018;: pubmed publisher |
Albers R, Selesniemi K, Natale D, Brown T. TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation. Int J Stem Cells. 2018;11:111-120 pubmed publisher |
Raykhel I, Moafi F, Myllym ki S, Greciano P, Matlin K, Moyano J, et al. BAMBI is a novel HIF1-dependent modulator of TGFβ-mediated disruption of cell polarity during hypoxia. J Cell Sci. 2018;131: pubmed publisher |
Wang C, Najm R, Xu Q, Jeong D, Walker D, Balestra M, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nat Med. 2018;24:647-657 pubmed publisher |
Fröhlich D, Suchowerska A, Voss C, He R, Wolvetang E, von Jonquieres G, et al. Expression Pattern of the Aspartyl-tRNA Synthetase DARS in the Human Brain. Front Mol Neurosci. 2018;11:81 pubmed publisher |
Smyth D, Harcus Y, White M, Gregory W, Nahler J, Stephens I, et al. TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus. Int J Parasitol. 2018;48:379-385 pubmed publisher |
Hsu F, Spannl S, Ferguson C, Hyman A, Parton R, Zerial M. Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria. elife. 2018;7: pubmed publisher |
Caires Júnior L, Goulart E, Melo U, Araujo B, Alvizi L, Soares Schanoski A, et al. Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells. Nat Commun. 2018;9:475 pubmed publisher |
Noskovičová N, Heinzelmann K, Burgstaller G, Behr J, Eickelberg O. Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol. 2018;314:L695-L707 pubmed publisher |
Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed publisher |
Bernard K, Logsdon N, Benavides G, SANDERS Y, Zhang J, Darley Usmar V, et al. Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation. J Biol Chem. 2018;293:1218-1228 pubmed publisher |
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed publisher |
Major T, Powers A, Tabar V. Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells. Curr Protoc Stem Cell Biol. 2017;39:1H.10.1-1H.10.23 pubmed publisher |
JACOB A, Morley M, Hawkins F, McCauley K, Jean J, Heins H, et al. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells. Cell Stem Cell. 2017;21:472-488.e10 pubmed publisher |
Park A, Havekes R, Fu X, Hansen R, Tudor J, Peixoto L, et al. Learning induces the translin/trax RNase complex to express activin receptors for persistent memory. elife. 2017;6: pubmed publisher |
Tchieu J, Zimmer B, Fattahi F, Amin S, Zeltner N, Chen S, et al. A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages. Cell Stem Cell. 2017;21:399-410.e7 pubmed publisher |
Funaki S, Shintani Y, Kawamura T, Kanzaki R, Minami M, Okumura M. Chemotherapy enhances programmed cell death 1/ligand 1 expression via TGF-β induced epithelial mesenchymal transition in non-small cell lung cancer. Oncol Rep. 2017;38:2277-2284 pubmed publisher |
Sloan S, Darmanis S, Huber N, Khan T, Birey F, Caneda C, et al. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells. Neuron. 2017;95:779-790.e6 pubmed publisher |
Bao X, Lian X, Qian T, Bhute V, Han T, Palecek S. Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions. Nat Protoc. 2017;12:1890-1900 pubmed publisher |
Takata K, Kozaki T, Lee C, Thion M, Otsuka M, Lim S, et al. Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function. Immunity. 2017;47:183-198.e6 pubmed publisher |
Song Y, Botvinnik O, Lovci M, Kakaradov B, Liu P, Xu J, et al. Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation. Mol Cell. 2017;67:148-161.e5 pubmed publisher |
Young F, Keruzore M, Nan X, Gennet N, Bellefroid E, Li M. The doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1. Proc Natl Acad Sci U S A. 2017;114:E5599-E5607 pubmed publisher |
Molina M, Quirin M, Haillot E, Jimenez F, Chessel A, Lepage T. p38 MAPK as an essential regulator of dorsal-ventral axis specification and skeletogenesis during sea urchin development: a re-evaluation. Development. 2017;144:2270-2281 pubmed publisher |
Yang Q, Yan C, Yin C, Gong Z. Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma. Cell Mol Gastroenterol Hepatol. 2017;3:484-499 pubmed publisher |
Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed publisher |
McCauley K, Hawkins F, Serra M, Thomas D, JACOB A, Kotton D. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 2017;20:844-857.e6 pubmed publisher |
Sampaziotis F, de Brito M, Geti I, Bertero A, Hannan N, Vallier L. Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells. Nat Protoc. 2017;12:814-827 pubmed publisher |
Charney R, Forouzmand E, Cho J, Cheung J, Paraiso K, Yasuoka Y, et al. Foxh1 Occupies cis-Regulatory Modules Prior to Dynamic Transcription Factor Interactions Controlling the Mesendoderm Gene Program. Dev Cell. 2017;40:595-607.e4 pubmed publisher |
de la Mare J, Jurgens T, Edkins A. Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model. BMC Cancer. 2017;17:202 pubmed publisher |
Xi H, Fujiwara W, Gonzalez K, Jan M, Liebscher S, Van Handel B, et al. In Vivo Human Somitogenesis Guides Somite Development from hPSCs. Cell Rep. 2017;18:1573-1585 pubmed publisher |
Kunnen S, Leonhard W, Semeins C, Hawinkels L, Poelma C, Ten Dijke P, et al. Fluid shear stress-induced TGF-?/ALK5 signaling in renal epithelial cells is modulated by MEK1/2. Cell Mol Life Sci. 2017;74:2283-2298 pubmed publisher |
Subramanian L, Bershteyn M, Paredes M, Kriegstein A. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun. 2017;8:14167 pubmed publisher |
Saini J, Corneo B, Miller J, Kiehl T, Wang Q, Boles N, et al. Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration. Cell Stem Cell. 2017;20:635-647.e7 pubmed publisher |
Guo X, Colon A, Akanda N, Spradling S, Stancescu M, Martin C, et al. Tissue engineering the mechanosensory circuit of the stretch reflex arc with human stem cells: Sensory neuron innervation of intrafusal muscle fibers. Biomaterials. 2017;122:179-187 pubmed publisher |
Bershteyn M, Nowakowski T, Pollen A, Di Lullo E, Nene A, Wynshaw Boris A, et al. Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. 2017;20:435-449.e4 pubmed publisher |
Christoforou N, Chakraborty S, Kirkton R, Adler A, Addis R, Leong K. Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage. Sci Rep. 2017;7:40285 pubmed publisher |
Offermann A, Vlasic I, Syring I, Vogel W, Ruiz C, Zellweger T, et al. MED15 overexpression in prostate cancer arises during androgen deprivation therapy via PI3K/mTOR signaling. Oncotarget. 2017;8:7964-7976 pubmed publisher |
Moerkamp A, Lodder K, van Herwaarden T, Dronkers E, Dingenouts C, Tengström F, et al. Human fetal and adult epicardial-derived cells: a novel model to study their activation. Stem Cell Res Ther. 2016;7:174 pubmed |
López de Maturana R, Lang V, Zubiarrain A, Sousa A, Vázquez N, Gorostidi A, et al. Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons. J Neuroinflammation. 2016;13:295 pubmed |
Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 2016;22:1421-1427 pubmed publisher |
Spender L, Ferguson G, Liu S, Cui C, Girotti M, Sibbet G, et al. Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells. Oncotarget. 2016;7:81995-82012 pubmed publisher |
Sulaiman A, Zolnierczyk K, Japa O, Owen J, Maddison B, Emes R, et al. A Trematode Parasite Derived Growth Factor Binds and Exerts Influences on Host Immune Functions via Host Cytokine Receptor Complexes. PLoS Pathog. 2016;12:e1005991 pubmed publisher |
Marro J, Pfefferli C, de Preux Charles A, Bise T, Jazwinska A. Collagen XII Contributes to Epicardial and Connective Tissues in the Zebrafish Heart during Ontogenesis and Regeneration. PLoS ONE. 2016;11:e0165497 pubmed publisher |
La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, et al. Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells. Cell. 2016;167:566-580.e19 pubmed publisher |
Ghaedi M, Niklason L. Human Pluripotent Stem Cells (iPSC) Generation, Culture, and Differentiation to Lung Progenitor Cells. Methods Mol Biol. 2016;: pubmed |
Topalovski M, Hagopian M, Wang M, Brekken R. Hypoxia and Transforming Growth Factor ? Cooperate to Induce Fibulin-5 Expression in Pancreatic Cancer. J Biol Chem. 2016;291:22244-22252 pubmed |
Nott A, Cheng J, Gao F, Lin Y, Gjoneska E, Ko T, et al. Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. Nat Neurosci. 2016;19:1497-1505 pubmed publisher |
Kapeli K, Pratt G, Vu A, Hutt K, Martinez F, Sundararaman B, et al. Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nat Commun. 2016;7:12143 pubmed publisher |
Locci M, Wu J, Arumemi F, Mikulski Z, Dahlberg C, Miller A, et al. Activin A programs the differentiation of human TFH cells. Nat Immunol. 2016;17:976-84 pubmed publisher |
Mou H, Vinarsky V, Tata P, Brazauskas K, Choi S, Crooke A, et al. Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells. Cell Stem Cell. 2016;19:217-231 pubmed publisher |
Genbacev O, Larocque N, Ona K, Prakobphol A, Garrido Gomez T, Kapidzic M, et al. Integrin ?4-positive human trophoblast progenitors: functional characterization and transcriptional regulation. Hum Reprod. 2016;31:1300-14 pubmed publisher |
Vargel O, Zhang Y, Kosim K, Ganter K, Foehr S, Mardenborough Y, et al. Activation of the TGFβ pathway impairs endothelial to haematopoietic transition. Sci Rep. 2016;6:21518 pubmed publisher |
Huang M, Miller M, McHenry L, Zheng T, Zhen Q, Ilkhanizadeh S, et al. Generating trunk neural crest from human pluripotent stem cells. Sci Rep. 2016;6:19727 pubmed publisher |
Morris M, Dawson C, Laverick L, Davis A, Dudman J, Raveenthiraraj S, et al. The Epstein-Barr virus encoded LMP1 oncoprotein modulates cell adhesion via regulation of activin A/TGFβ and β1 integrin signalling. Sci Rep. 2016;6:19533 pubmed publisher |
Lages Y, Nascimento J, Lemos G, Galina A, Castilho L, Rehen S. Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells. Peerj. 2015;3:e1486 pubmed publisher |
Ramnath N, Hawinkels L, van Heijningen P, te Riet L, Paauwe M, Vermeij M, et al. Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels. Sci Rep. 2015;5:16872 pubmed publisher |
Sakaguchi H, Kadoshima T, Soen M, Narii N, Ishida Y, Ohgushi M, et al. Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue. Nat Commun. 2015;6:8896 pubmed publisher |
Kumar N, Richter J, Cutts J, Bush K, Trujillo C, Nigam S, et al. Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. elife. 2015;4: pubmed publisher |
Imaizumi K, Sone T, Ibata K, Fujimori K, Yuzaki M, Akamatsu W, et al. Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes. Stem Cell Reports. 2015;5:1010-1022 pubmed publisher |
Buczek M, Miles A, Green W, Johnson C, Boocock D, Pockley A, et al. Cytoplasmic PML promotes TGF-β-associated epithelial-mesenchymal transition and invasion in prostate cancer. Oncogene. 2016;35:3465-75 pubmed publisher |
Ginsberg M, Schachterle W, Shido K, Rafii S. Direct conversion of human amniotic cells into endothelial cells without transitioning through a pluripotent state. Nat Protoc. 2015;10:1975-85 pubmed publisher |
Zhang L, Yin J, Yeh H, Ma N, Lee G, Chen X, et al. Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons. Cell Stem Cell. 2015;17:735-47 pubmed publisher |
Ziv O, Zaritsky A, Yaffe Y, Mutukula N, Edri R, Elkabetz Y. Quantitative Live Imaging of Human Embryonic Stem Cell Derived Neural Rosettes Reveals Structure-Function Dynamics Coupled to Cortical Development. PLoS Comput Biol. 2015;11:e1004453 pubmed publisher |
Jönsson M, Nelander Wahlestedt J, Akerblom M, Kirkeby A, Malmevik J, Brattaas P, et al. Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor. Development. 2015;142:3166-77 pubmed publisher |
Agu C, Soares F, Alderton A, Patel M, Ansari R, Patel S, et al. Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr. Stem Cell Reports. 2015;5:660-71 pubmed publisher |
Singh A, Sun Y, Li L, Zhang W, Wu T, Zhao S, et al. Cell-Cycle Control of Bivalent Epigenetic Domains Regulates the Exit from Pluripotency. Stem Cell Reports. 2015;5:323-36 pubmed publisher |
Rempel E, Hoelting L, Waldmann T, Balmer N, Schildknecht S, Grinberg M, et al. A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015;89:1599-618 pubmed publisher |
Iovino M, Agathou S, González Rueda A, Del Castillo Velasco Herrera M, Borroni B, Alberici A, et al. Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations. Brain. 2015;138:3345-59 pubmed publisher |
Hu Z, Pu J, Jiang H, Zhong P, Qiu J, Li F, et al. Generation of Naivetropic Induced Pluripotent Stem Cells from Parkinson's Disease Patients for High-Efficiency Genetic Manipulation and Disease Modeling. Stem Cells Dev. 2015;24:2591-604 pubmed publisher |
Sposito T, Preza E, Mahoney C, Setó Salvia N, Ryan N, Morris H, et al. Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT. Hum Mol Genet. 2015;24:5260-9 pubmed publisher |
Li D, Wang A, Liu X, Meisgen F, Grünler J, Botusan I, et al. MicroRNA-132 enhances transition from inflammation to proliferation during wound healing. J Clin Invest. 2015;125:3008-26 pubmed publisher |
Oh J, Lee K, Kim H, You Y, Yoon D, Song K, et al. Human-induced pluripotent stem cells generated from intervertebral disc cells improve neurologic functions in spinal cord injury. Stem Cell Res Ther. 2015;6:125 pubmed publisher |
Aspalter I, Gordon E, Dubrac A, Ragab A, Narloch J, Vizan P, et al. Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. Nat Commun. 2015;6:7264 pubmed publisher |
Caraci F, Gulisano W, Guida C, Impellizzeri A, Drago F, Puzzo D, et al. A key role for TGF-β1 in hippocampal synaptic plasticity and memory. Sci Rep. 2015;5:11252 pubmed publisher |
PaÅŸca A, Sloan S, Clarke L, Tian Y, Makinson C, Huber N, et al. Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nat Methods. 2015;12:671-8 pubmed publisher |
Kawahara T, Yamashita M, Ikegami K, Nakamura T, Yanagita M, Yamada S, et al. TGF-Beta Negatively Regulates the BMP2-Dependent Early Commitment of Periodontal Ligament Cells into Hard Tissue Forming Cells. PLoS ONE. 2015;10:e0125590 pubmed publisher |
Woods L, Camden J, El Sayed F, Khalafalla M, Petris M, Erb L, et al. Increased Expression of TGF-β Signaling Components in a Mouse Model of Fibrosis Induced by Submandibular Gland Duct Ligation. PLoS ONE. 2015;10:e0123641 pubmed publisher |
Soukup V, Yong L, Lu T, Huang S, Kozmik Z, Yu J. The Nodal signaling pathway controls left-right asymmetric development in amphioxus. Evodevo. 2015;6:5 pubmed publisher |
Cebola I, RodrÃguez Seguà S, Cho C, Bessa J, Rovira M, Luengo M, et al. TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors. Nat Cell Biol. 2015;17:615-626 pubmed publisher |
Wilson C, Ottewell P, Coleman R, Holen I. The differential anti-tumour effects of zoledronic acid in breast cancer - evidence for a role of the activin signaling pathway. BMC Cancer. 2015;15:55 pubmed publisher |
Chen Y, Chiang W, Yang Y, Lai C, Wu K, Lin S. Pentoxifylline Attenuates Proteinuria in Anti-Thy1 Glomerulonephritis via Downregulation of Nuclear Factor-?B and Smad2/3 Signaling. Mol Med. 2015;21:276-84 pubmed publisher |
Hadland B, Varnum Finney B, Poulos M, Moon R, Butler J, Rafii S, et al. Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells. J Clin Invest. 2015;125:2032-45 pubmed publisher |
Yan C, Huo X, Wang S, Feng Y, Gong Z. Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish. J Hepatol. 2015;63:420-8 pubmed publisher |
Fang J, Xu H, Yang C, Morsalin S, Kayarthodi S, Rungsrisuriyachai K, et al. Ets Related Gene and Smad3 Proteins Collaborate to Activate Transforming Growth Factor-Beta Mediated Signaling Pathway in ETS Related Gene-Positive Prostate Cancer Cells. J Pharm Sci Pharmacol. 2014;1:175-181 pubmed |
Tabata T, Petitt M, Zydek M, Fang Hoover J, Larocque N, Tsuge M, et al. Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta. J Virol. 2015;89:5134-47 pubmed publisher |
Piao J, Major T, Auyeung G, Policarpio E, Menon J, Droms L, et al. Human embryonic stem cell-derived oligodendrocyte progenitors remyelinate the brain and rescue behavioral deficits following radiation. Cell Stem Cell. 2015;16:198-210 pubmed publisher |
Sanders Y, Cui Z, Le Saux C, Horowitz J, Rangarajan S, Kurundkar A, et al. SMAD-independent down-regulation of caveolin-1 by TGF-β: effects on proliferation and survival of myofibroblasts. PLoS ONE. 2015;10:e0116995 pubmed publisher |
Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D Souza S, et al. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells. Nat Protoc. 2015;10:413-25 pubmed publisher |
Dai P, Harada Y, Miyachi H, Tanaka H, Kitano S, Adachi T, et al. Combining TGF-β signal inhibition and connexin43 silencing for iPSC induction from mouse cardiomyocytes. Sci Rep. 2014;4:7323 pubmed publisher |
MartÃnez Armenta M, DÃaz de León Guerrero S, Catalán A, Alvarez Arellano L, Uribe R, Subramaniam M, et al. TGFβ2 regulates hypothalamic Trh expression through the TGFβ inducible early gene-1 (TIEG1) during fetal development. Mol Cell Endocrinol. 2015;400:129-39 pubmed publisher |
Saporta M, Dang V, Volfson D, Zou B, Xie X, Adebola A, et al. Axonal Charcot-Marie-Tooth disease patient-derived motor neurons demonstrate disease-specific phenotypes including abnormal electrophysiological properties. Exp Neurol. 2015;263:190-9 pubmed publisher |
Wrighton P, Klim J, Hernandez B, Koonce C, Kamp T, Kiessling L. Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins. Proc Natl Acad Sci U S A. 2014;111:18126-31 pubmed publisher |
Ooi J, Hayden M, Pouladi M. Inhibition of Excessive Monoamine Oxidase A/B Activity Protects Against Stress-induced Neuronal Death in Huntington Disease. Mol Neurobiol. 2015;52:1850-1861 pubmed publisher |
Niederst E, Reyna S, Goldstein L. Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing. Mol Biol Cell. 2015;26:205-17 pubmed publisher |
Honsho K, Hirose M, Hatori M, Yasmin L, Izu H, Matoba S, et al. Naïve-like conversion enhances the difference in innate in vitro differentiation capacity between rabbit ES cells and iPS cells. J Reprod Dev. 2015;61:13-9 pubmed publisher |
Curado F, Spuul P, Egaña I, Rottiers P, Daubon T, Veillat V, et al. ALK5 and ALK1 play antagonistic roles in transforming growth factor β-induced podosome formation in aortic endothelial cells. Mol Cell Biol. 2014;34:4389-403 pubmed publisher |
Domev H, Milkov I, Itskovitz Eldor J, Dar A. Immunoevasive pericytes from human pluripotent stem cells preferentially modulate induction of allogeneic regulatory T cells. Stem Cells Transl Med. 2014;3:1169-81 pubmed publisher |
Le Bras G, Taylor C, Koumangoye R, Revetta F, Loomans H, Andl C. TGF? loss activates ADAMTS-1-mediated EGF-dependent invasion in a model of esophageal cell invasion. Exp Cell Res. 2015;330:29-42 pubmed publisher |
Aguila J, Blak A, van Arensbergen J, Sousa A, Vazquez N, Aduriz A, et al. Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells. Stem Cells Transl Med. 2014;3:1032-42 pubmed publisher |
Grunseich C, Zukosky K, Kats I, Ghosh L, Harmison G, Bott L, et al. Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients. Neurobiol Dis. 2014;70:12-20 pubmed publisher |
Wu K, Ren R, Su W, Wen B, Zhang Y, Yi F, et al. A novel suppressive effect of alcohol dehydrogenase 5 in neuronal differentiation. J Biol Chem. 2014;289:20193-9 pubmed publisher |
Chen J, Galloway J. The development of zebrafish tendon and ligament progenitors. Development. 2014;141:2035-45 pubmed publisher |
Rosa A, Papaioannou M, Krzyspiak J, Brivanlou A. miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells. Dev Biol. 2014;391:81-8 pubmed publisher |
Nishimura A, Shum C, Scotter E, Abdelgany A, Sardone V, Wright J, et al. Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells. PLoS ONE. 2014;9:e91269 pubmed publisher |
Li C, Peart N, Xuan Z, Lewis D, Xia Y, Jin J. PMA induces SnoN proteolysis and CD61 expression through an autocrine mechanism. Cell Signal. 2014;26:1369-78 pubmed publisher |
Suresh Babu S, Valdez Y, Xu A, O Byrne A, Calvo F, Lei V, et al. TGF?-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells. BMC Cancer. 2014;14:113 pubmed publisher |
O Reilly S, Ciechomska M, Cant R, van Laar J. Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-? (TGF-?) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem. 2014;289:9952-60 pubmed publisher |
Valdez Magaña G, Rodriguez A, Zhang H, Webb R, Alberio R. Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation. Dev Biol. 2014;387:15-27 pubmed publisher |
Soares F, Chandra A, Thomas R, Pedersen R, Vallier L, Williams D. Investigating the feasibility of scale up and automation of human induced pluripotent stem cells cultured in aggregates in feeder free conditions. J Biotechnol. 2014;173:53-8 pubmed publisher |
Rafiei S, Komarova S. Molecular signaling pathways mediating osteoclastogenesis induced by prostate cancer cells. BMC Cancer. 2013;13:605 pubmed publisher |
Huang S, Islam M, O NEILL J, Hu Z, Yang Y, Chen Y, et al. Efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol. 2014;32:84-91 pubmed publisher |
Xie Q, Shen Z, Oh J, Chu H, Malter J. Transforming Growth Factor-β1 Antagonizes Interleukin-5 Pro-Survival Signaling by Activating Calpain-1 in Primary Human Eosinophils. J Clin Cell Immunol. 2011;Suppl 1: pubmed |
Woodruff G, Young J, Martinez F, Buen F, Gore A, Kinaga J, et al. The presenilin-1 ?E9 mutation results in reduced ?-secretase activity, but not total loss of PS1 function, in isogenic human stem cells. Cell Rep. 2013;5:974-85 pubmed publisher |
Bialas A, Stevens B. TGF-? signaling regulates neuronal C1q expression and developmental synaptic refinement. Nat Neurosci. 2013;16:1773-82 pubmed publisher |
Orlova V, Drabsch Y, Freund C, Petrus Reurer S, van den Hil F, Muenthaisong S, et al. Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts. Arterioscler Thromb Vasc Biol. 2014;34:177-86 pubmed publisher |
Marlow R, Honeth G, Lombardi S, Cariati M, Hessey S, Pipili A, et al. A novel model of dormancy for bone metastatic breast cancer cells. Cancer Res. 2013;73:6886-99 pubmed publisher |
Razak S, Ueno K, Takayama N, Nariai N, Nagasaki M, Saito R, et al. Profiling of microRNA in human and mouse ES and iPS cells reveals overlapping but distinct microRNA expression patterns. PLoS ONE. 2013;8:e73532 pubmed publisher |
Lee Chang C, Bodogai M, Martin Montalvo A, Wejksza K, Sanghvi M, Moaddel R, et al. Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells. J Immunol. 2013;191:4141-51 pubmed publisher |
McQualter J, McCarty R, Van der Velden J, O Donoghue R, Asselin Labat M, Bozinovski S, et al. TGF-β signaling in stromal cells acts upstream of FGF-10 to regulate epithelial stem cell growth in the adult lung. Stem Cell Res. 2013;11:1222-33 pubmed publisher |
Crompton L, Byrne M, Taylor H, Kerrigan T, Bru Mercier G, Badger J, et al. Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling. Stem Cell Res. 2013;11:1206-21 pubmed publisher |
Voon D, Wang H, Koo J, Chai J, Hor Y, Tan T, et al. EMT-induced stemness and tumorigenicity are fueled by the EGFR/Ras pathway. PLoS ONE. 2013;8:e70427 pubmed publisher |
Kim K, Park J, Jo S, Jung S, Kwon O, Gallerano G, et al. High-power femtosecond-terahertz pulse induces a wound response in mouse skin. Sci Rep. 2013;3:2296 pubmed publisher |
Honda A, Hatori M, Hirose M, Honda C, Izu H, Inoue K, et al. Naive-like conversion overcomes the limited differentiation capacity of induced pluripotent stem cells. J Biol Chem. 2013;288:26157-66 pubmed publisher |
Jiang J, Jing Y, Cost G, Chiang J, Kolpa H, Cotton A, et al. Translating dosage compensation to trisomy 21. Nature. 2013;500:296-300 pubmed publisher |
Kreitzer F, Salomonis N, Sheehan A, Huang M, Park J, Spindler M, et al. A robust method to derive functional neural crest cells from human pluripotent stem cells. Am J Stem Cells. 2013;2:119-31 pubmed |
Kusuma S, Shen Y, Hanjaya Putra D, Mali P, Cheng L, Gerecht S. Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix. Proc Natl Acad Sci U S A. 2013;110:12601-6 pubmed publisher |
Oenema T, Maarsingh H, Smit M, Groothuis G, Meurs H, Gosens R. Bronchoconstriction Induces TGF-? Release and Airway Remodelling in Guinea Pig Lung Slices. PLoS ONE. 2013;8:e65580 pubmed publisher |
Xia M, Huang R, Sakamuru S, Alcorta D, Cho M, Lee D, et al. Identification of repurposed small molecule drugs for chordoma therapy. Cancer Biol Ther. 2013;14:638-47 pubmed publisher |
Shields M, Ebine K, Sahai V, Kumar K, Siddiqui K, Hwang R, et al. Snail cooperates with KrasG12D to promote pancreatic fibrosis. Mol Cancer Res. 2013;11:1078-87 pubmed publisher |
Chetty S, Pagliuca F, Honore C, Kweudjeu A, Rezania A, Melton D. A simple tool to improve pluripotent stem cell differentiation. Nat Methods. 2013;10:553-6 pubmed publisher |
Davila J, Chanda S, Ang C, Sudhof T, Wernig M. Acute reduction in oxygen tension enhances the induction of neurons from human fibroblasts. J Neurosci Methods. 2013;216:104-9 pubmed publisher |
Pol S, Lang J, O Bara M, Cimato T, McCallion A, Sim F. Sox10-MCS5 enhancer dynamically tracks human oligodendrocyte progenitor fate. Exp Neurol. 2013;247:694-702 pubmed publisher |
Briones Orta M, Levy L, Madsen C, Das D, Erker Y, Sahai E, et al. Arkadia regulates tumor metastasis by modulation of the TGF-? pathway. Cancer Res. 2013;73:1800-10 pubmed publisher |
Lotz S, Goderie S, Tokas N, Hirsch S, Ahmad F, Corneo B, et al. Sustained levels of FGF2 maintain undifferentiated stem cell cultures with biweekly feeding. PLoS ONE. 2013;8:e56289 pubmed publisher |
Shalom Feuerstein R, Serror L, Aberdam E, Muller F, van Bokhoven H, Wiman K, et al. Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET. Proc Natl Acad Sci U S A. 2013;110:2152-6 pubmed publisher |
Kirkeby A, Nelander J, Parmar M. Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Front Cell Neurosci. 2012;6:64 pubmed publisher |
Spender L, Carter M, O Brien D, Clark L, Yu J, Michalak E, et al. Transforming growth factor-? directly induces p53-up-regulated modulator of apoptosis (PUMA) during the rapid induction of apoptosis in myc-driven B-cell lymphomas. J Biol Chem. 2013;288:5198-209 pubmed publisher |
Hoda M, Münzker J, Ghanim B, Schelch K, Klikovits T, Laszlo V, et al. Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells. Br J Cancer. 2012;107:1978-86 pubmed publisher |
Rodriguez A, Allegrucci C, Alberio R. Modulation of pluripotency in the porcine embryo and iPS cells. PLoS ONE. 2012;7:e49079 pubmed publisher |
Valdez J, Zhang L, Su Q, Dakhova O, Zhang Y, Shahi P, et al. Notch and TGF? form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity. Cell Stem Cell. 2012;11:676-88 pubmed publisher |
Patsialou A, Wang Y, Lin J, Whitney K, Goswami S, Kenny P, et al. Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients. Breast Cancer Res. 2012;14:R139 pubmed publisher |
Sohni A, Mulas F, Ferrazzi F, Luttun A, Bellazzi R, Huylebroeck D, et al. TGF?1-induced Baf60c regulates both smooth muscle cell commitment and quiescence. PLoS ONE. 2012;7:e47629 pubmed publisher |
Boeuf S, Bovee J, Lehner B, van den Akker B, van Ruler M, Cleton Jansen A, et al. BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors. BMC Cancer. 2012;12:488 pubmed publisher |
Luo Y, Su Y. Opposing nodal and BMP signals regulate left-right asymmetry in the sea urchin larva. PLoS Biol. 2012;10:e1001402 pubmed publisher |
Denham M, Bye C, Leung J, Conley B, Thompson L, Dottori M. Glycogen synthase kinase 3? and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage. Stem Cells. 2012;30:2400-11 pubmed publisher |
Neely M, Litt M, Tidball A, Li G, Aboud A, Hopkins C, et al. DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. ACS Chem Neurosci. 2012;3:482-91 pubmed publisher |
Rostovskaya M, Fu J, Obst M, Baer I, Weidlich S, Wang H, et al. Transposon-mediated BAC transgenesis in human ES cells. Nucleic Acids Res. 2012;40:e150 pubmed publisher |
Smith P, Tanaka H, Chantry A. A novel co-operative mechanism linking TGF? and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells. Oncotarget. 2012;3:518-24 pubmed |
Boettler T, Cheng Y, Ehrhardt K, von Herrath M. TGF-? blockade does not improve control of an established persistent viral infection. Viral Immunol. 2012;25:232-8 pubmed publisher |
Grönroos E, Kingston I, Ramachandran A, Randall R, Vizan P, Hill C. Transforming growth factor ? inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes. Mol Cell Biol. 2012;32:2904-16 pubmed publisher |
Mak S, Huang Y, Iranmanesh S, Vangipuram M, Sundararajan R, Nguyen L, et al. Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage. Stem Cells Int. 2012;2012:140427 pubmed publisher |
Outten J, Gadue P, French D, Diamond S. High-throughput screening assay for embryoid body differentiation of human embryonic stem cells. Curr Protoc Stem Cell Biol. 2012;Chapter 1:Unit 1D.6 pubmed publisher |
Shi Y, Kirwan P, Smith J, Robinson H, Livesey F. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci. 2012;15:477-86, S1 pubmed publisher |
Varela C, Denis J, Polentes J, Feyeux M, Aubert S, Champon B, et al. Recurrent genomic instability of chromosome 1q in neural derivatives of human embryonic stem cells. J Clin Invest. 2012;122:569-74 pubmed publisher |
Xi Q, Wang Z, Zaromytidou A, Zhang X, Chow Tsang L, Liu J, et al. A poised chromatin platform for TGF-? access to master regulators. Cell. 2011;147:1511-24 pubmed publisher |
Wilson E, El Jawhari J, Neilson A, Hall G, Melcher A, Meade J, et al. Human tumour immune evasion via TGF-? blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity. PLoS ONE. 2011;6:e22842 pubmed publisher |
Paek H, Hwang J, Zukin R, Hebert J. ?-Catenin-dependent FGF signaling sustains cell survival in the anterior embryonic head by countering Smad4. Dev Cell. 2011;20:689-99 pubmed publisher |
Kurita Y, Wada H. Evidence that gastropod torsion is driven by asymmetric cell proliferation activated by TGF-beta signalling. Biol Lett. 2011;7:759-62 pubmed publisher |
Herman Edelstein M, Thomas M, Thallas Bonke V, Saleem M, Cooper M, Kantharidis P. Dedifferentiation of immortalized human podocytes in response to transforming growth factor-?: a model for diabetic podocytopathy. Diabetes. 2011;60:1779-88 pubmed publisher |
Seibler P, Graziotto J, Jeong H, Simunovic F, Klein C, Krainc D. Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells. J Neurosci. 2011;31:5970-6 pubmed publisher |
Grocott T, Johnson S, Bailey A, Streit A. Neural crest cells organize the eye via TGF-β and canonical Wnt signalling. Nat Commun. 2011;2:265 pubmed publisher |
Chen Y, Leask A, Abraham D, Kennedy L, Shi wen X, Denton C, et al. Thrombospondin 1 is a key mediator of transforming growth factor ?-mediated cell contractility in systemic sclerosis via a mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)-dependent mechanism. Fibrogenesis Tissue Repair. 2011;4:9 pubmed publisher |
Olkhanud P, Damdinsuren B, Bodogai M, Gress R, Sen R, Wejksza K, et al. Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4⺠T cells to T-regulatory cells. Cancer Res. 2011;71:3505-15 pubmed publisher |
Hecker L, Jagirdar R, Jin T, Thannickal V. Reversible differentiation of myofibroblasts by MyoD. Exp Cell Res. 2011;317:1914-21 pubmed publisher |
Tan T, Tang X, Zhang J, Niu Y, Chen H, Li B, et al. Generation of trophoblast stem cells from rabbit embryonic stem cells with BMP4. PLoS ONE. 2011;6:e17124 pubmed publisher |
Duan C, Cao Y, Deng X, Wang W, Yang W, Liu X, et al. Increased transforming growth factor β contributes to deterioration of refrigerated fresh frozen plasma's effects in vitro on endothelial cells. Shock. 2011;36:54-9 pubmed publisher |
Shields M, Dangi Garimella S, Krantz S, Bentrem D, Munshi H. Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion. J Biol Chem. 2011;286:10495-504 pubmed publisher |
Bedel R, Thiery Vuillemin A, Grandclement C, Balland J, Remy Martin J, Kantelip B, et al. Novel role for STAT3 in transcriptional regulation of NK immune cell targeting receptor MICA on cancer cells. Cancer Res. 2011;71:1615-26 pubmed publisher |
Krueger C, Hoffmann F. Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. PLoS ONE. 2010;5:e15511 pubmed publisher |
Holley R, Pickford C, Rushton G, Lacaud G, Gallagher J, Kouskoff V, et al. Influencing hematopoietic differentiation of mouse embryonic stem cells using soluble heparin and heparan sulfate saccharides. J Biol Chem. 2011;286:6241-52 pubmed publisher |
Dangi Garimella S, Strouch M, Grippo P, Bentrem D, Munshi H. Collagen regulation of let-7 in pancreatic cancer involves TGF-?1-mediated membrane type 1-matrix metalloproteinase expression. Oncogene. 2011;30:1002-8 pubmed publisher |
Moyano J, Greciano P, Buschmann M, Koch M, Matlin K. Autocrine transforming growth factor-{beta}1 activation mediated by integrin {alpha}V{beta}3 regulates transcriptional expression of laminin-332 in Madin-Darby canine kidney epithelial cells. Mol Biol Cell. 2010;21:3654-68 pubmed publisher |
Fong J, Le Nihouannen D, Komarova S. Tumor-supportive and osteoclastogenic changes induced by breast cancer-derived factors are reversed by inhibition of {gamma}-secretase. J Biol Chem. 2010;285:31427-34 pubmed publisher |
Ewan K, Pajak B, Stubbs M, Todd H, Barbeau O, Quevedo C, et al. A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Res. 2010;70:5963-73 pubmed publisher |
Hannigan A, Smith P, Kalna G, Lo Nigro C, Orange C, O Brien D, et al. Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter. J Clin Invest. 2010;120:2842-57 pubmed publisher |
Redondo S, Ruiz E, Gordillo Moscoso A, Navarro Dorado J, Ramajo M, Carnero M, et al. Role of TGF-beta1 and MAP kinases in the antiproliferative effect of aspirin in human vascular smooth muscle cells. PLoS ONE. 2010;5:e9800 pubmed publisher |
Alberio R, Croxall N, Allegrucci C. Pig epiblast stem cells depend on activin/nodal signaling for pluripotency and self-renewal. Stem Cells Dev. 2010;19:1627-36 pubmed publisher |
Wang X, McLennan S, Allen T, Twigg S. Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes. J Cell Commun Signal. 2010;4:15-23 pubmed publisher |
Ishida T, Nakajima T, Kudo A, Kawakami A. Phosphorylation of Junb family proteins by the Jun N-terminal kinase supports tissue regeneration in zebrafish. Dev Biol. 2010;340:468-79 pubmed publisher |
James D, Nam H, Seandel M, Nolan D, Janovitz T, Tomishima M, et al. Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nat Biotechnol. 2010;28:161-6 pubmed publisher |
Patsialou A, Wyckoff J, Wang Y, Goswami S, Stanley E, Condeelis J. Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor. Cancer Res. 2009;69:9498-506 pubmed publisher |
Li W, Zhou H, Abujarour R, Zhu S, Young Joo J, Lin T, et al. Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells. 2009;27:2992-3000 pubmed publisher |
Giampieri S, Manning C, Hooper S, Jones L, Hill C, Sahai E. Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat Cell Biol. 2009;11:1287-96 pubmed publisher |
Patani R, Compston A, Puddifoot C, Wyllie D, Hardingham G, Allen N, et al. Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity. PLoS ONE. 2009;4:e7327 pubmed publisher |
Waghabi M, de Souza E, de Oliveira G, Keramidas M, Feige J, Araujo Jorge T, et al. Pharmacological inhibition of transforming growth factor beta signaling decreases infection and prevents heart damage in acute Chagas' disease. Antimicrob Agents Chemother. 2009;53:4694-701 pubmed publisher |
Cacheaux L, Ivens S, David Y, Lakhter A, Bar Klein G, Shapira M, et al. Transcriptome profiling reveals TGF-beta signaling involvement in epileptogenesis. J Neurosci. 2009;29:8927-35 pubmed publisher |
Ham S, Kim H, Kim H, Kang E, Eun S, Kim G, et al. PPARdelta promotes wound healing by up-regulating TGF-beta1-dependent or -independent expression of extracellular matrix proteins. J Cell Mol Med. 2010;14:1747-59 pubmed publisher |
Roussigné M, Bianco I, Wilson S, Blader P. Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei. Development. 2009;136:1549-57 pubmed publisher |
Walshe T, Saint Geniez M, Maharaj A, Sekiyama E, Maldonado A, D Amore P. TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature. PLoS ONE. 2009;4:e5149 pubmed publisher |
Garamszegi N, Garamszegi S, Shehadeh L, Scully S. Extracellular matrix-induced gene expression in human breast cancer cells. Mol Cancer Res. 2009;7:319-29 pubmed publisher |
Chambers S, Fasano C, Papapetrou E, Tomishima M, Sadelain M, Studer L. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol. 2009;27:275-80 pubmed publisher |
Clarke D, Brown M, Erickson R, Shi Y, Liu X. Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics. Mol Cell Biol. 2009;29:2443-55 pubmed publisher |
Grande C, Patel N. Nodal signalling is involved in left-right asymmetry in snails. Nature. 2009;457:1007-11 pubmed publisher |
Xiao Y, Liu K, Shen J, Xu G, Ye W. SB-431542 inhibition of scar formation after filtration surgery and its potential mechanism. Invest Ophthalmol Vis Sci. 2009;50:1698-706 pubmed publisher |
Ding W, Warburton D. Down-regulation of Sprouty2 via p38 MAPK plays a key role in the induction of cellular apoptosis by tumor necrosis factor-alpha. Biochem Biophys Res Commun. 2008;375:460-4 pubmed publisher |
Yang J, Song K, Krebs T, Jackson M, Danielpour D. Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression. Oncogene. 2008;27:5326-38 pubmed publisher |
Stoikos C, Harrison C, Salamonsen L, Dimitriadis E. A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. Hum Reprod. 2008;23:1447-56 pubmed publisher |
Bharathy S, Xie W, Yingling J, Reiss M. Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype. Cancer Res. 2008;68:1656-66 pubmed publisher |
Gressner O, Lahme B, Siluschek M, Rehbein K, Herrmann J, Weiskirchen R, et al. Activation of TGF-beta within cultured hepatocytes and in liver injury leads to intracrine signaling with expression of connective tissue growth factor. J Cell Mol Med. 2008;12:2717-30 pubmed publisher |
Ho D, Whitman M. TGF-beta signaling is required for multiple processes during Xenopus tail regeneration. Dev Biol. 2008;315:203-16 pubmed publisher |
Zhu W, Xu P, Cuascut F, Hall A, Oxford G. Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I. J Neurosci. 2007;27:13770-80 pubmed |
Lévesque M, Gatien S, Finnson K, Desmeules S, Villiard E, Pilote M, et al. Transforming growth factor: beta signaling is essential for limb regeneration in axolotls. PLoS ONE. 2007;2:e1227 pubmed |
Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, et al. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood. 2008;111:1933-41 pubmed |
Hagos E, Fan X, Dougan S. The role of maternal Activin-like signals in zebrafish embryos. Dev Biol. 2007;309:245-58 pubmed |
Dai P, Nakagami T, Tanaka H, Hitomi T, Takamatsu T. Cx43 mediates TGF-beta signaling through competitive Smads binding to microtubules. Mol Biol Cell. 2007;18:2264-73 pubmed |
Castañares C, Redondo Horcajo M, Magán Marchal N, Ten Dijke P, Lamas S, Rodriguez Pascual F. Signaling by ALK5 mediates TGF-beta-induced ET-1 expression in endothelial cells: a role for migration and proliferation. J Cell Sci. 2007;120:1256-66 pubmed |
Montesano R, Carrozzino F, Soulie P. Low concentrations of transforming growth factor-beta-1 induce tubulogenesis in cultured mammary epithelial cells. BMC Dev Biol. 2007;7:7 pubmed |
Ivens S, Kaufer D, Flores L, Bechmann I, Zumsteg D, Tomkins O, et al. TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis. Brain. 2007;130:535-47 pubmed |
Horowitz J, Rogers D, Sharma V, Vittal R, White E, Cui Z, et al. Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts. Cell Signal. 2007;19:761-71 pubmed |
Zhao C, Chen W, Yang L, Chen L, Stimpson S, Diehl A. PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells. Biochem Biophys Res Commun. 2006;350:385-91 pubmed |
Shi wen X, Rodriguez Pascual F, Lamas S, Holmes A, Howat S, Pearson J, et al. Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors. Mol Cell Biol. 2006;26:5518-27 pubmed |
Ninomiya K, Takahashi A, Fujioka Y, Ishikawa Y, Yokoyama M. Transforming growth factor-beta signaling enhances transdifferentiation of macrophages into smooth muscle-like cells. Hypertens Res. 2006;29:269-76 pubmed |
Ho D, Chan J, Bayliss P, Whitman M. Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo. Dev Biol. 2006;295:730-42 pubmed |
Chen H, Shen J, Ip Y, Xu L. Identification of phosphatases for Smad in the BMP/DPP pathway. Genes Dev. 2006;20:648-53 pubmed |
Chen Y, Shi wen X, van Beek J, Kennedy L, McLeod M, Renzoni E, et al. Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease. Am J Pathol. 2005;167:1699-711 pubmed |
Anumanthan G, Halder S, Osada H, Takahashi T, Massion P, Carbone D, et al. Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells. Br J Cancer. 2005;93:1157-67 pubmed |
Mimura K, Kono K, Hanawa M, Kanzaki M, Nakao A, Ooi A, et al. Trastuzumab-mediated antibody-dependent cellular cytotoxicity against esophageal squamous cell carcinoma. Clin Cancer Res. 2005;11:4898-904 pubmed |
König H, Kogel D, Rami A, Prehn J. TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling. J Cell Biol. 2005;168:1077-86 pubmed |
