pep2-SVKI | Tocris Bioscience 1597 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

pep2-SVKI

catalog :

1597

quantity :

2 mg

price :

161 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Grey K, Burrell B. Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases. J Neurophysiol. 2010;103:2737-46 pubmed publisher
McElligott Z, Klug J, Nobis W, Patel S, Grueter B, Kash T, et al. Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress. Proc Natl Acad Sci U S A. 2010;107:2271-6 pubmed publisher
Dickinson B, Jo J, Seok H, Son G, Whitcomb D, Davies C, et al. A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha. Mol Brain. 2009;2:18 pubmed publisher
Xia Y, Nawy S, Carroll R. Activity-dependent synaptic plasticity in retinal ganglion cells. J Neurosci. 2007;27:12221-9 pubmed

product information

brand :

Tocris

master code :

1597

SKU :

1597/2

product name :

pep2-SVKI

description :

Peptide inhibitor of GluA2 subunit binding to GRIP, ABP and PICK1; increases AMPA current amplitude

target :

AMPA Receptor Inhibitors

category :

Peptides

unit size :

2 mg

observed molecular weight :

1284.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD). . Control Peptide also available.

catalog number base :

1597

product keywords :

Peptide inhibitors inhibits GluR2 subunit binding GRIP ABP PICK1 Increases AMPA current amplitude Glutamate Receptors iGlur Ionotropic GluA2 AMPA Receptors 1597,

extended description :

Peptide inhibitor of GluA2 subunit binding to GRIP, ABP and PICK1; increases AMPA current amplitude

formula :

C 60 H 93 N 13 O 18

formula text :

C60H93N13O18

cas num :

328944-75-8

2020 USD :

161

2021 USD :

161 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage