| Reference |
|---|
Martin J, Sheehan J, Bratton B, Moore G, Mateus A, Li S, et al. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. Cell. 2020;181:1518-1532.e14 pubmed publisher |
Noskovičová N, Heinzelmann K, Burgstaller G, Behr J, Eickelberg O. Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol. 2018;314:L695-L707 pubmed publisher |
Zhang S, Liu Y, WANG Z, Liu J, Gu Z, Xu Q, et al. PAR1‑mediated c‑Jun activation promotes heat stress‑induced early stage apoptosis of human umbilical vein endothelial cells. Mol Med Rep. 2017;15:2595-2603 pubmed publisher |
Li Y, Yang W, Quinones Hinojosa A, Wang B, Xu S, Zhu W, et al. Interference with Protease-activated Receptor 1 Alleviates Neuronal Cell Death Induced by Lipopolysaccharide-Stimulated Microglial Cells through the PI3K/Akt Pathway. Sci Rep. 2016;6:38247 pubmed publisher |
Al Gwairi O, Osman N, Getachew R, Zheng W, Liang X, Kamato D, et al. Multiple Growth Factors, But Not VEGF, Stimulate Glycosaminoglycan Hyperelongation in Retinal Choroidal Endothelial Cells. Int J Biol Sci. 2016;12:1041-51 pubmed publisher |
Auvergne R, Wu C, Connell A, Au S, Cornwell A, Osipovitch M, et al. PAR1 inhibition suppresses the self-renewal and growth of A2B5-defined glioma progenitor cells and their derived gliomas in vivo. Oncogene. 2016;35:3817-28 pubmed publisher |
Carrim N, Arthur J, Hamilton J, Gardiner E, Andrews R, Moran N, et al. Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα. Redox Biol. 2015;6:640-647 pubmed publisher |
Gur Cohen S, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, et al. PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nat Med. 2015;21:1307-17 pubmed publisher |
Otsuki T, Fujimoto D, Hirono Y, Goi T, Yamaguchi A. Thrombin conducts epithelial‑mesenchymal transition via protease‑activated receptor‑1 in human gastric cancer. Int J Oncol. 2014;45:2287-94 pubmed publisher |
Tripathi T, Abdi M, Alizadeh H. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014;55:3912-21 pubmed publisher |
Yang H, Li T, Wei J, Zhang H, He S. Induction of tumor necrosis factor (TNF) release from subtypes of T cells by agonists of proteinase activated receptors. Mediators Inflamm. 2013;2013:165453 pubmed publisher |
Gadepalli R, Kotla S, Heckle M, Verma S, Singh N, Rao G. Novel role for p21-activated kinase 2 in thrombin-induced monocyte migration. J Biol Chem. 2013;288:30815-31 pubmed publisher |
Juncker Jensen A, Deryugina E, Rimann I, Zajac E, Kupriyanova T, Engelholm L, et al. Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination. Cancer Res. 2013;73:4196-211 pubmed publisher |
Yan J, Manaenko A, Chen S, Klebe D, Ma Q, Caner B, et al. Role of SCH79797 in maintaining vascular integrity in rat model of subarachnoid hemorrhage. Stroke. 2013;44:1410-7 pubmed publisher |
Ganachari M, Guio H, Zhao N, Flores Villanueva P. Host gene-encoded severe lung TB: from genes to the potential pathways. Genes Immun. 2012;13:605-20 pubmed publisher |
Chen B, Friedman B, Whitney M, Winkle J, Lei I, Olson E, et al. Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci. 2012;32:7622-31 pubmed publisher |
Scarisbrick I, Radulovic M, Burda J, Larson N, Blaber S, Giannini C, et al. Kallikrein 6 is a novel molecular trigger of reactive astrogliosis. Biol Chem. 2012;393:355-67 pubmed publisher |
Okamura Y, Schmidt R, Raschke I, Hintze M, Takeoka S, Egner A, et al. A few immobilized thrombins are sufficient for platelet spreading. Biophys J. 2011;100:1855-63 pubmed publisher |
Dowal L, Sim D, Dilks J, Blair P, Beaudry S, Denker B, et al. Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1. Proc Natl Acad Sci U S A. 2011;108:2951-6 pubmed publisher |
Vidwan P, Pathak A, Sheth S, Huang J, Monroe D, Stouffer G. Activation of protease-activated receptors 3 and 4 accelerates tissue factor-induced thrombin generation on the surface of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2010;30:2587-96 pubmed publisher |
Fujimoto D, Hirono Y, Goi T, Katayama K, Matsukawa S, Yamaguchi A. The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion. BMC Cancer. 2010;10:443 pubmed publisher |
Lee E, Woo M, Moon P, Baek M, Choi I, Kim W, et al. Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1. J Immunol. 2010;185:615-23 pubmed publisher |
Malik G, Knowles L, Dhir R, Xu S, Yang S, Ruoslahti E, et al. Plasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasion. Cancer Res. 2010;70:4327-34 pubmed publisher |
Yoshikawa Y, Hirayasu H, Tsuzuki S, Fushiki T. Granzyme A and thrombin differentially promote the release of interleukin-8 from alveolar epithelial A549 cells. Cytotechnology. 2010;62:325-32 pubmed publisher |
Blackburn J, Liu I, Coon C, Brinckerhoff C. A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis. Oncogene. 2009;28:4237-48 pubmed publisher |
Popovic M, Laumonnier Y, Burysek L, Syrovets T, Simmet T. Thrombin-induced expression of endothelial CX3CL1 potentiates monocyte CCL2 production and transendothelial migration. J Leukoc Biol. 2008;84:215-23 pubmed publisher |
Ma L, Perini R, McKnight W, Dicay M, Klein A, Hollenberg M, et al. Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets. Proc Natl Acad Sci U S A. 2005;102:216-20 pubmed |
