product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
NBI 27914 hydrochloride
catalog :
1591/10
quantity :
10 mg (also 50 mg)
price :
219 USD
more info or order :
citations: 12
Reference |
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Gutknecht E, Hauger R, Van der Linden I, Vauquelin G, Dautzenberg F. Expression, binding, and signaling properties of CRF2(a) receptors endogenously expressed in human retinoblastoma Y79 cells: passage-dependent regulation of functional receptors. J Neurochem. 2008;104:926-36 pubmed
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Gallopin T, Geoffroy H, Rossier J, Lambolez B. Cortical sources of CRF, NKB, and CCK and their effects on pyramidal cells in the neocortex. Cereb Cortex. 2006;16:1440-52 pubmed
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product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1591
SKU :
1591/10
product name :
NBI 27914 hydrochloride
description :
Selective non-peptide CRF1 antagonist
target :
CRF1 Receptor Antagonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Store at RT
observed molecular weight :
470.66
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
NBI 27914 hydrochloride is a selective, non-peptide corticotropin-releasing factor1 (CRF1) receptor antagonist (Ki = 1.7 nM); has no activity at CRF2 receptors. Blocks behavioral seizures in vivo .
product keywords :
Selective non-peptide CRF1 antagonists Corticotropin-Releasing Factor1 Receptors NBI27914 hydrochloride CRF1 Receptors 1591,
extended description :
Selective non-peptide CRF1 antagonist
chemical name text :
5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N -(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride
formula :
C18H20Cl4N4.HCl
formula text :
C18H20Cl4N4.HCl
cas num :
1215766-76-9
USD :
216
USD 2025 :
219 USD
product details :
Selective non-peptide CRF1 antagonist
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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