Radicicol | Tocris Bioscience 1589 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Radicicol

catalog :

1589

quantity :

1 mg

price :

147 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Ginzberg M, Chang N, D Souza H, Patel N, Kafri R, Kirschner M. Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity. elife. 2018;7: pubmed publisher
Stecklein S, Kumaraswamy E, Behbod F, Wang W, Chaguturu V, HARLAN WILLIAMS L, et al. BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation. Proc Natl Acad Sci U S A. 2012;109:13650-5 pubmed publisher

product information

brand :

Tocris

master code :

1589

SKU :

1589/1

product name :

Radicicol

description :

Hsp90 inhibitor. Antifungal antibiotic

target :

HSP90 Inhibitors

category :

Small Molecules

unit size :

1 mg

main entrez gene id :

3320

purity :

98%

observed molecular weight :

364.78

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antifungal antibiotic. Inhibits heat shock protein 90 (Hsp90) activity by binding to the ATP-binding pocket, subsequently suppressing cell transformation induced by src, ras and mos. Represses estrogen receptor transcriptional activity and inhibits angiogenesis.

catalog number base :

1589

product keywords :

Hsp90 inhibitors inhibits Antifungal antibiotics Heat Shock Proteins 90 Hsp90 Antibiotics Antifungals 1589,

extended description :

Hsp90 inhibitor. Antifungal antibiotic

chemical name text :

(1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione

formula :

C 18 H 17 ClO 6

formula text :

C18H17ClO6

cas num :

12772-57-5

2020 USD :

142

2021 USD :

147 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage