product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Piceatannol
catalog :
1554
quantity :
10 mg
price :
195 USD
more info or order :
citations: 8
Reference
Shin K, Kataru R, Park H, Kwon B, Kim T, Hong Y, et al. TH2 cells and their cytokines regulate formation and function of lymphatic vessels. Nat Commun. 2015;6:6196 pubmed publisher
Bakema J, Tuk C, van Vliet S, Bruijns S, Vos J, Letsiou S, et al. Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs. J Immunol. 2015;194:1856-66 pubmed publisher
Verma A, Kroetz D, Tweedle J, Deepe G. Type II cytokines impair host defense against an intracellular fungal pathogen by amplifying macrophage generation of IL-33. Mucosal Immunol. 2015;8:380-9 pubmed publisher
Mitrugno A, Williams D, Kerrigan S, Moran N. A novel and essential role for Fc?RIIa in cancer cell-induced platelet activation. Blood. 2014;123:249-60 pubmed publisher
Farrand L, Byun S, Kim J, Im aram A, Lee J, Lim S, et al. Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission. J Biol Chem. 2013;288:23740-50 pubmed publisher
Siddoway B, Altimimi H, Hou H, Petralia R, Xu B, Stellwagen D, et al. An essential role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling. J Neurosci. 2013;33:11206-11 pubmed publisher
Meyer J, Ejendal K, Avramova L, Garland Kuntz E, Giraldo Calder n G, Brust T, et al. A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptors. PLoS Negl Trop Dis. 2012;6:e1478 pubmed publisher
Dierks C, Adrian F, Fisch P, Ma H, Maurer H, Herchenbach D, et al. The ITK-SYK fusion oncogene induces a T-cell lymphoproliferative disease in mice mimicking human disease. Cancer Res. 2010;70:6193-204 pubmed publisher
product information
brand :
Tocris
master code :
1554
SKU :
1554/10
product name :
Piceatannol
description :
Inhibits TNF-induced NF- B activation
target :
NFkB/IkB Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
98%
observed molecular weight :
244.25
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56lck and syk protein tyrosine kinases and inhibits TNF-induced NF- B activation and gene expression. Synthesis results from conversion of resveratrol (Cat. No. 1418) by cytochrome P450 1B1.
catalog number base :
1554
product keywords :
Syk p56lck kinase inhibitors inhibits TNF-induced NF- B NF-kappaB NF-kB activation Kinases Nuclear Factor Kappa B Cytokine Signaling Signalling Transcription Factors Src Kinases Syk Kinase NF-kB/IkB 1554,
extended description :
Inhibits TNF-induced NF- B activation
chemical name text :
4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,2-benzenediol
formula :
C 14 H 12 O 4
formula text :
C14H12O4
cas num :
10083-24-6
2020 USD :
187
2021 USD :
195 USD
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK