Piceatannol | Tocris Bioscience 1554/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Piceatannol

catalog :

1554/10

quantity :

10 mg

price :

245 USD

citations: 10

Reference
Shin K, Kataru R, Park H, Kwon B, Kim T, Hong Y, et al. TH2 cells and their cytokines regulate formation and function of lymphatic vessels. Nat Commun. 2015;6:6196 pubmed publisher
Bakema J, Tuk C, van Vliet S, Bruijns S, Vos J, Letsiou S, et al. Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs. J Immunol. 2015;194:1856-66 pubmed publisher
Verma A, Kroetz D, Tweedle J, Deepe G. Type II cytokines impair host defense against an intracellular fungal pathogen by amplifying macrophage generation of IL-33. Mucosal Immunol. 2015;8:380-9 pubmed publisher
Mitrugno A, Williams D, Kerrigan S, Moran N. A novel and essential role for Fc?RIIa in cancer cell-induced platelet activation. Blood. 2014;123:249-60 pubmed publisher
Goggs R, Harper M, Pope R, Savage J, Williams C, Mundell S, et al. RhoG protein regulates platelet granule secretion and thrombus formation in mice. J Biol Chem. 2013;288:34217-29 pubmed publisher
Farrand L, Byun S, Kim J, Im aram A, Lee J, Lim S, et al. Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission. J Biol Chem. 2013;288:23740-50 pubmed publisher
Siddoway B, Altimimi H, Hou H, Petralia R, Xu B, Stellwagen D, et al. An essential role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling. J Neurosci. 2013;33:11206-11 pubmed publisher
Giegold O, Ogrissek N, Richter C, Schröder M, Herrero San Juan M, Pfeilschifter J, et al. CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation. J Immunol. 2013;190:3696-705 pubmed publisher
Meyer J, Ejendal K, Avramova L, Garland Kuntz E, Giraldo Calder n G, Brust T, et al. A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptors. PLoS Negl Trop Dis. 2012;6:e1478 pubmed publisher
Dierks C, Adrian F, Fisch P, Ma H, Maurer H, Herchenbach D, et al. The ITK-SYK fusion oncogene induces a T-cell lymphoproliferative disease in mice mimicking human disease. Cancer Res. 2010;70:6193-204 pubmed publisher

product information

brand :

Tocris

master code :

1554

SKU :

1554/10

product name :

Piceatannol

unit size :

10 mg

seo description :

Inhibits TNF-induced NF- B activation

target :

NFkB/IkB Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

244.25

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56lck and syk protein tyrosine kinases and inhibits TNF-induced NF- B activation and gene expression. Synthesis results from conversion of resveratrol (Cat. No. 1418) by cytochrome P450 1B1.

top caption :

Inhibits TNF-induced NF- B activation

extended description :

Inhibits TNF-induced NF- B activation

chemical name text :

4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,2-benzenediol

formula :

C14H12O4

formula text :

C14H12O4

cas num :

10083-24-6

USD :

245 USD

product details :

Inhibits TNF-induced NF- B activation

storage :

Store at +4░C