product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SC 560
catalog :
1550/10
quantity :
10 mg
price :
225 USD
more info or order :
citations: 2
Reference
Gaertner S, Auger C, Farooq M, Pollet B, Khemais Benkhiat S, Niazi Z, et al. Oral Intake of EPA:DHA 6:1 by Middle-Aged Rats for One Week Improves Age-Related Endothelial Dysfunction in Both the Femoral Artery and Vein: Role of Cyclooxygenases. Int J Mol Sci. 2020;21: pubmed publisher
Fritz M, Klawonn A, Nilsson A, Singh A, Zajdel J, Wilhelms D, et al. Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice. J Clin Invest. 2016;126:695-705 pubmed
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1550
SKU :
1550/10
product name :
SC 560
description :
Cyclooxygenase-1 (COX-1) inhibitor
target :
Cyclooxygenase Inhibitors
unit size :
10 mg
category :
Small Molecules
purity :
98%
storage :
Store at +4°C
observed molecular weight :
352.74
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SC 560 is a highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.009 and 6.3 u M for COX-1 and COX-2 respectively). Inhibits COX-1-derived platelet thromboxane B2, gastric PGE2 and dermal PDE2 production. Significantly reduces ovarian surface epithelial tumor growth in vivo . Orally active.
product keywords :
Cyclooxygenase COX-1 inhibitors inhibits Oxygenases Oxidases SC560 Cyclooxygenase 1550,
extended description :
Cyclooxygenase-1 (COX-1) inhibitor
chemical name text :
5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
formula :
C17H12ClF3N2O
formula text :
C17H12ClF3N2O
cas num :
188817-13-2
USD :
222
USD 2025 :
225 USD
product details :
Cyclooxygenase-1 (COX-1) inhibitor
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK