Cantharidin | Tocris Bioscience 1548/50 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cantharidin

catalog :

1548/50

quantity :

50 mg

price :

157 USD

citations: 5

Reference
Lang C, Campbell K, Ryan B, Carling P, Attar M, Vowles J, et al. Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes. Cell Stem Cell. 2019;24:93-106.e6 pubmed publisher
Shuhaibar L, Robinson J, Vigone G, Shuhaibar N, Egbert J, Baena V, et al. Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor. elife. 2017;6: pubmed publisher
Polito M, Guiot E, Gangarossa G, Longueville S, Doulazmi M, Valjent E, et al. Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3). Eneuro. 2015;2: pubmed publisher
Egbert J, Shuhaibar L, Edmund A, Van Helden D, Robinson J, Uliasz T, et al. Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes. Development. 2014;141:3594-604 pubmed publisher
Gray E, Guglietta R, Khakh B, O Dell T. Inhibitory interactions between phosphorylation sites in the C terminus of ?-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor GluA1 subunits. J Biol Chem. 2014;289:14600-11 pubmed publisher

product information

brand :

Tocris

master code :

1548

SKU :

1548/50

product name :

Cantharidin

unit size :

50 mg

description :

The Recombinant Human TROY/TNFRSF19 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TROY/TNFRSF19 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Protein Ser/Thr Phosphatase Inhibitors

category :

Small Molecules

storage :

Store at RT

observed molecular weight :

196.2

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cantharidin is a natural toxin inhibitor of protein phosphatases 1 and 2A (Ki values are 1.1 and 0.19 u M respectively); similar to okadaic acid (Cat. No. 1136). Displays 500-fold selectivity over PP2B.

extended description :

Protein phosphatase 1 and 2A inhibitor

chemical name text :

(3a ,4 ,7 ,7a )-Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione

formula :

C 10 H 12 O 4

formula text :

C10H12O4

cas num :

56-25-7

USD :

150

Jul-22 :

157 USD

product details :

Protein phosphatase 1 and 2A inhibitor

sizes available :

50 mg