NSC 95397 | Tocris Bioscience 1547/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NSC 95397

catalog :

1547/10

quantity :

10 mg (also 50 mg)

price :

275 USD

citations: 1

Reference
Dulyaninova N, Hite K, Zencheck W, Scudiero D, Almo S, Shoemaker R, et al. Cysteine 81 is critical for the interaction of S100A4 and myosin-IIA. Biochemistry. 2011;50:7218-27 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

1547

SKU :

1547/10

product name :

NSC 95397

Description :

Selective Cdc25 dual specificity phosphatase inhibitor

target :

Cdc25 Phosphatase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

310.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NSC 95397 is a potent and selective irreversible inhibitor of Cdc25 dual specificity phosphatases (Ki values are 32, 96 and 40 nM for inhibition of Cdc25A, -B and -C respectively). Displays 125 - 180-fold selectivity over VH1-related dual-specificity phosphatase and protein tyrosine phosphatase 1b. Inhibits carcinoma cell growth and blocks G2/M phase transition in vitro .

extended description :

Selective Cdc25 dual specificity phosphatase inhibitor

chemical name text :

2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone

formula :

C 14 H 14 O 4 S 2

formula text :

C14H14O4S2

cas num :

93718-83-3

USD :

275 USD

product details :

Selective Cdc25 dual specificity phosphatase inhibitor

storage :

Desiccate at -20°C