(S)-(-)-Bay K 8644 | Tocris Bioscience 1546 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(S)-(-)-Bay K 8644

catalog :

1546

quantity :

10 mg (also 50 mg)

price :

314 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Alles S, Garcia E, Balasubramanyan S, Jones K, Tyson J, Joy T, et al. Peripheral nerve injury increases contribution of L-type calcium channels to synaptic transmission in spinal lamina II: Role of α2δ-1 subunits. Mol Pain. 2018;14:1744806918765806 pubmed publisher
Wei X, Yu S, Ren L, Huang S, Yang Q, Wang P, et al. Inhibition of late sodium current suppresses calcium-related ventricular arrhythmias by reducing the phosphorylation of CaMK-II and sodium channel expressions. Sci Rep. 2017;7:981 pubmed publisher
Burtscher V, Schicker K, Novikova E, Pohn B, Stockner T, Kugler C, et al. Spectrum of Cav1.4 dysfunction in congenital stationary night blindness type 2. Biochim Biophys Acta. 2014;1838:2053-65 pubmed publisher
Chen F, Liu Y, Sugiura Y, Allen P, Gregg R, Lin W. Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors. Nat Neurosci. 2011;14:570-7 pubmed publisher
Landstrom A, Kellen C, Dixit S, van Oort R, Garbino A, Weisleder N, et al. Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling. Circ Heart Fail. 2011;4:214-23 pubmed publisher

product information

brand :

Tocris

master code :

1546

SKU :

1546/10

product name :

(S)-(-)-Bay K 8644

description :

CaV1.x activator; (S)-(-)-enantiomer of ( )-Bay K 8644

target :

Voltage-gated Calcium Channel Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

356.3

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo . . Racemate and ( R )-(+)-Enantiomer also available.

catalog number base :

1546

product keywords :

Ca2+-channel activators L-type Calcium CaV Channels L-Type voltage-gated voltage-dependent Ca2+ (S)-(-)-BayK8644 Cav1.x Channels 1546, Voltage-gated calcium channel activator, voltage gated calcium channel, high-voltage activated Ca2+ channel, high voltage gated ca2+ channel

extended description :

CaV1.x activator; (S)-(-)-enantiomer of ( )-Bay K 8644

chemical name text :

(4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester

formula :

C 16 H 15 F 3 N 2 O 4

formula text :

C16H15F3N2O4

cas num :

98625-26-4

2020 USD :

301

2021 USD :

314 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage