(S)-(-)-Bay K 8644 | Tocris Bioscience 1546/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(S)-(-)-Bay K 8644

catalog :

1546/10

quantity :

10 mg (also 50 mg)

price :

391 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Alles S, Garcia E, Balasubramanyan S, Jones K, Tyson J, Joy T, et al. Peripheral nerve injury increases contribution of L-type calcium channels to synaptic transmission in spinal lamina II: Role of α2δ-1 subunits. Mol Pain. 2018;14:1744806918765806 pubmed publisher
Wei X, Yu S, Ren L, Huang S, Yang Q, Wang P, et al. Inhibition of late sodium current suppresses calcium-related ventricular arrhythmias by reducing the phosphorylation of CaMK-II and sodium channel expressions. Sci Rep. 2017;7:981 pubmed publisher
Burtscher V, Schicker K, Novikova E, Pohn B, Stockner T, Kugler C, et al. Spectrum of Cav1.4 dysfunction in congenital stationary night blindness type 2. Biochim Biophys Acta. 2014;1838:2053-65 pubmed publisher
Chen F, Liu Y, Sugiura Y, Allen P, Gregg R, Lin W. Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors. Nat Neurosci. 2011;14:570-7 pubmed publisher
Landstrom A, Kellen C, Dixit S, van Oort R, Garbino A, Weisleder N, et al. Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling. Circ Heart Fail. 2011;4:214-23 pubmed publisher

product information

brand :

Tocris

MasterCode :

1546

SKU :

1546/10

product name :

(S)-(-)-Bay K 8644

target :

Cav1.x Channel Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

356.3

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

( S )-(-)-Bay K 8644 is a L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo . . Racemate and ( R )-(+)-Enantiomer also available.

extended description :

CaV1.x activator; (S)-(-)-enantiomer of ( )-Bay K 8644

chemical name text :

(4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester

formula :

C 16 H 15 F 3 N 2 O 4

formula text :

C16H15F3N2O4

cas num :

98625-26-4

USD :

391 USD

product details :

CaV1.x activator; (S)-(-)-enantiomer of ( )-Bay K 8644

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage