Splitomicin | Tocris Bioscience 1542 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Splitomicin

catalog :

1542

quantity :

10 mg (also 50 mg)

price :

108 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Stavrou E, Fang C, Merkulova A, Alhalabi O, Grobe N, Antoniak S, et al. Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor. Blood. 2015;125:710-9 pubmed publisher
Kumari D, Usdin K. Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription. Hum Mol Genet. 2014;23:6575-83 pubmed publisher

product information

brand :

Tocris

master code :

1542

SKU :

1542/10

product name :

Splitomicin

description :

Sir2p inhibitor

target :

Class III Histone Deacetylases Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

198.22

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of Sir2p (IC50 = 60 u M), an NAD+-dependent Sir2 family deacetylase required for chromatin-dependent silencing in yeast.

catalog number base :

1542

product keywords :

Sir2p inhibitors inhibits Sirtuin Sir2-like Family Deacetylases Class III HDACs (Sirtuins) 1542,

extended description :

Sir2p inhibitor

chemical name text :

1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one

formula :

C 13 H 10 O 2

formula text :

C13H10O2

cas num :

3/9/90

2020 USD :

135

2021 USD :

108 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage