HA14-1 | Tocris Bioscience 1541/5 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HA14-1

catalog :

1541/5

quantity :

5 mg (also 25 mg)

price :

72 USD

citations: 2

Reference
Qin X, Cui J, Zhang Y. Coeloglossum viride var. bracteatum extract protects against amyloid toxicity in rat prefrontal cortex neurons. Int J Clin Exp Med. 2010;3:88-94 pubmed
Mohan N, Karmakar S, Choudhury S, Banik N, Ray S. Bcl-2 inhibitor HA14-1 and genistein together adeptly down regulated survival factors and activated cysteine proteases for apoptosis in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells. Brain Res. 2009;1283:155-66 pubmed publisher

product information

brand :

Tocris

SKU :

1541/5

product name :

HA14-1

unit sizes :

5 mg (also 25 mg)

description :

Bcl-2 inhibitor. Induces apoptosis

target :

Bcl-2 Family Inhibitors

category :

Small Molecules

storage :

Desiccate at -20°C

observed molecular weight :

409.23

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cell-permeable inhibitor of Bcl-2 protein (IC50 ~ 9 u M); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. Also binds to the antiapoptotic Blc-2 proteins Bcl-XL and Bcl-w.

catalog number base :

1541

extended description :

Bcl-2 inhibitor. Induces apoptosis

chemical name text :

2-Amino-6-bromo- -cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester

formula :

C 17 H 17 BrN 2 O 5

formula text :

C17H17BrN2O5

cas num :

65673-63-4

USD :

72 USD

default size :

TRUE

product details :

Bcl-2 inhibitor. Induces apoptosis