10Z-Hymenialdisine | Tocris Bioscience 1532/500 product information

product summary

request information :

company name :

Tocris Bioscience

product type :

chemical

product name :

10Z-Hymenialdisine

catalog :

1532/500

quantity :

500µg

price :

315 USD

more info or order :

Tocris Bioscience product webpage

product information

CHEMISTRY :

O=C(NCC1)C2=C(C=C(Br)N2)/C1=C3/C(N=C(N)N3)=O

Cat Number :

1532/500

Product Name :

10Z-Hymenialdisine

Cas Number :

[82005-12-7]

Unit Size :

500µg

Size :

500

Unit :

µg

USD :

315 USD

Primary Category :

Enzymes

Secondary Category :

Kinases

Tertiary Category :

MEK

Primary Action :

Pan kinase inhibitor; potently inhibits MEK1

Biological Description :

Pan kinase inhibitor (IC50 values are 6, 10, 22, 28, 35, 40, 70, 80, 100, 470, 500, 600, 700 and 700 nM for MEK1, GSK-3β, Cdk1/cyclin B, Cdk5/p25, CK1, Cdk2/cyclin A, Cdk2/cyclin E, ASK-γ, Cdk3/cyclin E, Erk1, PKCγ, Cdk4/cyclin D1, Cdk6/cyclin D2 and PKCα respectively.) Inhibits NF-κB activation and blocks IL-8 production in U937 cells (IC50 values are 1-2 and 0.34-0.48 μM respectively).

Formula :

C11H10BrN5O2

Molwt :

324.13

Synonyms :

SK&F 108752

more info or order :

Tocris Bioscience product webpage