LY 215840 | Tocris Bioscience 1523 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LY 215840

catalog :

1523

quantity :

10 mg (also 50 mg)

price :

199 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Chan J, McCorvy J, Acharya S, Johns M, Day T, Roth B, et al. A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. PLoS Pathog. 2016;12:e1005651 pubmed publisher
Chan J, Agbedanu P, Grab T, Zamanian M, Dosa P, Day T, et al. Ergot Alkaloids (Re)generate New Leads as Antiparasitics. PLoS Negl Trop Dis. 2015;9:e0004063 pubmed publisher
Watts S, Darios E, Seitz B, Thompson J. 5-HT is a potent relaxant in rat superior mesenteric veins. Pharmacol Res Perspect. 2015;3:e00103 pubmed publisher
Du Y, Cramer M, Lee C, Tang J, Muthusamy A, Antonetti D, et al. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J. 2015;29:2194-204 pubmed publisher

product information

brand :

Tocris

master code :

1523

SKU :

1523/10

product name :

LY 215840

description :

5-HT2/5-HT7 antagonist

target :

Non-selective 5-HT Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

395.54

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

5-HT2/5-HT7 receptor antagonist. Reduces stimulatory effect of serotonin on aldosterone secretion; also reduces 5-HT-induced cAMP formation (pKB = 8.26).

catalog number base :

1523

product keywords :

LY215840 5-ht serotonin receptors antagonists 5ht2 5ht7 5-hydroxytryptamine Non-selective 5-HT Non-selective 5-HT2 5-HT7 Receptors 1523,

extended description :

5-HT2/5-HT7 antagonist

chemical name text :

[8 (1S,2R)]-N-(2-Hydroxycyclopentyl)-6-methyl-1-(1-methylethyl)-ergoline-8-carboxamide

formula :

C 24 H 33 N 3 O 2

formula text :

C24H33N3O2

cas num :

137328-52-0

2020 USD :

199

2021 USD :

199 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage