SB 205384 | Tocris Bioscience 1512 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 205384

catalog :

1512

quantity :

10 mg (also 50 mg)

price :

141 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Heidelberg L, Warren J, Fisher J. SB-205384 is a positive allosteric modulator of recombinant GABAA receptors containing rat ?3, ?5, or ?6 subunit subtypes coexpressed with ?3 and ?2 subunits. J Pharmacol Exp Ther. 2013;347:235-41 pubmed publisher
Miller B, Schultz L, Long B, Pletcher M. Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice. Mamm Genome. 2010;21:247-57 pubmed publisher

product information

brand :

Tocris

master code :

1512

SKU :

1512/10

product name :

SB 205384

description :

GABAA modulator; slows current decay

target :

GABA-A Receptor Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

330.4

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GABAA receptor modulator; slows current decay. Potentiates 6, 3 and 5-subunit-containing receptors (EC50 values are 280, 695 and 730 nM respectively). Displays little effect on receptors containing 1 or 2 subunits.

catalog number base :

1512

product keywords :

GABAA receptor modulators slows current decay Receptors SB205384 GABAA Receptors 1512,

extended description :

GABAA modulator; slows current decay

chemical name text :

4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-[1H]benzothieno[2,3-b]pyridine-3-carboxylic acid 2-butynyl ester

formula :

C 17 H 18 N 2 O 3 S

formula text :

C17H18N2O3S

cas num :

160296-13-9

2020 USD :

138

2021 USD :

141 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage