product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SR 59230A hydrochloride
catalog :
1511/10
quantity :
10 mg (also 50 mg)
price :
274 USD
more info or order :
citations: 14
Reference |
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Armaiz Pena G, Gonzalez Villasana V, Nagaraja A, Rodriguez Aguayo C, Sadaoui N, Stone R, et al. Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth. Oncotarget. 2015;6:4266-73 pubmed
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Maupoil V, Bronquard C, Freslon J, Cosnay P, Findlay I. Ectopic activity in the rat pulmonary vein can arise from simultaneous activation of alpha1- and beta1-adrenoceptors. Br J Pharmacol. 2007;150:899-905 pubmed
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Nackley A, Tan K, Fecho K, Flood P, Diatchenko L, Maixner W. Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. Pain. 2007;128:199-208 pubmed
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Cirino G, Sorrentino R, di Villa Bianca R, Popolo A, Palmieri A, Imbimbo C, et al. Involvement of beta 3-adrenergic receptor activation via cyclic GMP- but not NO-dependent mechanisms in human corpus cavernosum function. Proc Natl Acad Sci U S A. 2003;100:5531-6 pubmed
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product information
brand :
Tocris
MasterCode :
1511
SKU :
1511/10
product name :
SR 59230A hydrochloride
target :
Adrenergic beta-3 Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
361.91
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SR 59230A hydrochloride is a potent and selective 3 adrenoceptor antagonist (IC50 values are 40, 408 and 648 nM for 3, 1 and 2 receptors respectively). Orally active in vivo .
extended description :
Potent and selective 3 antagonist
chemical name text :
1-(2-Ethylphenoxy)-3-[[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]-(2S)-2-propanol hydrochloride
formula :
C 21 H 27 NO 2 .HCl
formula text :
C21H27NO2.HCl
cas num :
1135278-41-9
USD :
274 USD
product details :
Potent and selective 3 antagonist
storage :
Store at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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