Ozagrel hydrochloride | Tocris Bioscience 1510/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ozagrel hydrochloride

catalog :

1510/10

quantity :

10 mg (also 50 mg)

price :

104 USD

citations: 2

Reference
Wong S, Leung F, Lau C, Au C, Yung L, Yao X, et al. Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging. Circ Res. 2009;104:228-35 pubmed publisher
Rancillac A, Rossier J, Guille M, Tong X, Geoffroy H, Amatore C, et al. Glutamatergic Control of Microvascular Tone by Distinct GABA Neurons in the Cerebellum. J Neurosci. 2006;26:6997-7006 pubmed

product information

brand :

Tocris

MasterCode :

1510

SKU :

1510/10

product name :

Ozagrel hydrochloride

unit sizes :

10 mg (also 50 mg)

description :

Selective thromboxane A2 synthetase inhibitor

target :

Additional Prostanoid Receptor Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

264.71

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ozagrel hydrochloride is a potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM). Does not inhibit prostacyclin (PGI2) synthetase, cyclooxygenase or PGE2 isomerase (IC50 1 mM). Inhibits platelet aggregation in vitro and arachidonate-induced arterial contraction in vivo .

extended description :

Selective thromboxane A2 synthetase inhibitor

chemical name text :

(2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid hydrochloride

formula :

C 13 H 12 N 2 O 2 .HCl

formula text :

C13H12N2O2.HCl

cas num :

78712-43-3

USD :

104 USD

product details :

Selective thromboxane A2 synthetase inhibitor

alt names :

OKY 046

storage :

Store at RT