FR 122047 hydrochloride | Tocris Bioscience 1507/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FR 122047 hydrochloride

catalog :

1507/10

quantity :

10 mg (also 50 mg)

price :

216 USD

citations: 6

Reference
Tunaru S, Chennupati R, Nusing R, Offermanns S. Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor. PLoS ONE. 2016;11:e0163633 pubmed publisher
Lu L, Sun H, Zhang W, Chai Z, Zhu X, Kong L, et al. Aspirin minimized the pro-metastasis effect of sorafenib and improved survival by up-regulating HTATIP2 in hepatocellular carcinoma. PLoS ONE. 2013;8:e65023 pubmed publisher
Tunaru S, Althoff T, Nusing R, Diener M, Offermanns S. Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors. Proc Natl Acad Sci U S A. 2012;109:9179-84 pubmed publisher
Passafaro D, Sterin Borda L, Reina S, Borda E. Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland. Dent Res J (Isfahan). 2011;8:138-45 pubmed
Chia E, Kagota S, Wijekoon E, McGuire J. Protection of protease-activated receptor 2 mediated vasodilatation against angiotensin II-induced vascular dysfunction in mice. BMC Pharmacol. 2011;11:10 pubmed publisher
Ray N, Bisher M, Enquist L. Cyclooxygenase-1 and -2 are required for production of infectious pseudorabies virus. J Virol. 2004;78:12964-74 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1507

SKU :

1507/10

product name :

FR 122047 hydrochloride

description :

Cyclooxygenase (COX-1) inhibitor

target :

Cyclooxygenase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Desiccate at +4°C

observed molecular weight :

459.99

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

FR 122047 hydrochloride is a selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.028 and 65 u M for COX-1 and COX-2 respectively). Antiplatelet, analgesic and anti-inflammatory following oral administration in vivo .

product keywords :

Cyclooxygenase COX-1 inhibitors inhibits Oxygenases Oxidases FR122047 hydrochloride Cyclooxygenase 1507,

extended description :

Cyclooxygenase (COX-1) inhibitor

chemical name text :

1-[[4,5-bis(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride

formula :

C23H25N3O3S.HCl

formula text :

C23H25N3O3S.HCl

cas num :

130717-51-0

USD :

240

USD 2025 :

216 USD

product details :

Cyclooxygenase (COX-1) inhibitor