product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Terazosin hydrochloride
catalog :
1506
quantity :
50 mg
price :
128 USD
more info or order :
citations: 2
Reference
Assad Kahn S, Costa S, Gholamin S, Nitta R, Dubois L, Fève M, et al. The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway. EMBO Mol Med. 2016;8:511-26 pubmed publisher
Bucher E, Fox M, Kim L, Kirkpatrick D, Rodeberg N, Belle A, et al. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis. J Cereb Blood Flow Metab. 2014;34:1128-37 pubmed publisher
product information
brand :
Tocris
master code :
1506
SKU :
1506/50
product name :
Terazosin hydrochloride
description :
1 and 2B antagonist ( 1 2B). Orally active
target :
Adrenergic alpha-1 Receptor Antagonists
category :
Small Molecules
unit size :
50 mg
purity :
99%
observed molecular weight :
423.9
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
1- and 2B-adrenoceptor antagonist (Ki values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for 1A, 1B, 1D, 2B, 2A and 2C receptors respectively). Antihypertensive following oral or intravenous administration in vivo .
catalog number base :
1506
product keywords :
1-adrenoceptor alpha1-adrenoceptor a1-adrenoceptor 2B-adrenoceptor alpha2B-adrenoceptor a2b-adrenoceptor a1-adrenergic 1-adrenergic alpha1-adrenergic a2a-adrenergic alpha2a-adrenergic antagonists Orally active Receptors Adrenergic Alpha-1 Receptors 1506,
extended description :
1 and 2B antagonist ( 1 2B). Orally active
chemical name text :
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride
formula :
C 19 H 25 N 5 O 4 .HCl
formula text :
C19H25N5O4.HCl
cas num :
63074-08-8
2020 USD :
123
2021 USD :
128 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK