Rimcazole dihydrochloride | Tocris Bioscience 1497/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Rimcazole dihydrochloride

catalog :

1497/10

quantity :

10 mg (also 50 mg)

price :

227 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rennekamp A, Huang X, Wang Y, Patel S, Lorello P, Cade L, et al. ?1 receptor ligands control a switch between passive and active threat responses. Nat Chem Biol. 2016;12:552-8 pubmed publisher

product information

brand :

Tocris

MasterCode :

1497

SKU :

1497/10

product name :

Rimcazole dihydrochloride

target :

Sigma2 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

394.39

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Rimcazole dihydrochloride is an antagonist at receptors (IC50 values are 1480 and 386 nM at 1 and 2 receptors respectively). Also binds to the dopamine transporter (IC50 = 57.6 nM) and inhibits dopamine uptake. Reduces the stimulatory effects of cocaine in vivo .

extended description :

2 antagonist. Also DAT inhibitor

chemical name text :

9-[3-(cis-3,5-Dimethyl-1-piperazinyl)propyl]-9H-carbazole dihydrochloride

formula :

C 21 H 27 N 3 .2HCl

formula text :

C21H27N3.2HCl

cas num :

75859-03-9

USD :

227 USD

product details :

2 antagonist. Also DAT inhibitor

alt names :

BW 234U

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage