CGP 78608 hydrochloride | Tocris Bioscience 1493/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CGP 78608 hydrochloride

catalog :

1493/10

quantity :

10 mg (also 50 mg)

price :

283 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

MasterCode :

1493

SKU :

1493/10

product name :

CGP 78608 hydrochloride

target :

NMDA Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

414.58

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CGP 78608 hydrochloride is a potent and selective NMDA antagonist that acts through the glycine site (IC50 = 5 nM). Displays 500-fold selectivity over kainate and AMPA receptors (IC50 values are 2.7 and 3 u M respectively). Also potentiates GluN1/GluN3A-mediated glycine currents (EC50 = 26.3 nM). Anticonvulsant in vivo following systemic administration.

extended description :

Potent and selective NMDA antagonist; acts at glycine site

chemical name text :

[(1S)-1-[[(7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]phosphonic acid hydrochloride

formula :

C 11 H 13 BrN 3 O 5 P.HCl

formula text :

C11H13BrN3O5P.HCl

cas num :

1135278-54-4

USD :

283 USD

product details :

Potent and selective NMDA antagonist; acts at glycine site

alt names :

PAMQX

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage