product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
AY-NH2
catalog :
1487/1
quantity :
1 mg
price :
390 USD
more info or order :
citations: 4
Reference
de la Fuente M, Han X, Miyagi M, Nieman M. Expression and Purification of Protease-Activated Receptor 4 (PAR4) and Analysis with Histidine Hydrogen-Deuterium Exchange. Biochemistry. 2020;59:671-681 pubmed publisher
Peng Q, Ratnasothy K, Boardman D, Jacob J, Tung S, McCluskey D, et al. Protease Activated Receptor 4 as a Novel Modulator of Regulatory T Cell Function. Front Immunol. 2019;10:1311 pubmed publisher
Wang H, Ricklin D, Lambris J. Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4. Proc Natl Acad Sci U S A. 2017;114:10948-10953 pubmed publisher
Shi H, Liu C, Ding L, Zheng Y, Fei X, Lu L, et al. Alterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction. World J Gastroenterol. 2015;21:4852-63 pubmed publisher
product information
brand :
Tocris
MasterCode :
1487
SKU :
1487/1
product name :
AY-NH2
target :
Protease-Activated Receptor Agonists
category :
Peptides
unit size :
1 mg
purity :
95%
observed molecular weight :
680.8
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
AY-NH2 is a selective PAR4 receptor agonist peptide. Stimulates platelet aggregation in vitro (EC50 = 15 u M). Exhibits an increase in paw thickness in the paw edema inflammation model in vivo .
extended description :
Selective PAR4 agonist
formula :
C 34 H 48 N 8 O 7
formula text :
C34H48N8O7
cas num :
352017-71-1
USD :
390 USD
product details :
Selective PAR4 agonist
alt names :
AYPGKF-NH2
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK