product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Oleylethanolamide
catalog :
1484/10
quantity :
10 mg (also 50 mg)
price :
129 USD
more info or order :
citations: 4
Reference
Silva Peña D, Rivera P, Alen F, Vargas A, Rubio L, García Marchena N, et al. Oleoylethanolamide Modulates BDNF-ERK Signaling and Neurogenesis in the Hippocampi of Rats Exposed to Δ9-THC and Ethanol Binge Drinking During Adolescence. Front Mol Neurosci. 2019;12:96 pubmed publisher
Suarez J, Rivera P, Arrabal S, Crespillo A, Serrano A, Baixeras E, et al. Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat. Dis Model Mech. 2014;7:129-41 pubmed publisher
Ropero A, Juan Pico P, Rafacho A, Fuentes E, Bermúdez Silva F, Roche E, et al. Rapid non-genomic regulation of Ca2+ signals and insulin secretion by PPAR alpha ligands in mouse pancreatic islets of Langerhans. J Endocrinol. 2009;200:127-38 pubmed publisher
Ho W, Barrett D, Randall M. 'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors. Br J Pharmacol. 2008;155:837-46 pubmed publisher
product information
brand :
Tocris
MasterCode :
1484
SKU :
1484/10
product name :
Oleylethanolamide
target :
GPR55 Receptor Agonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
325.53
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Oleylethanolamide is a lipid mediator and analog of anandamide (Cat. No. 1339) that is involved in peripheral regulation of feeding. Selective GPR55 agonist (EC50 values are 0.44, 30 and 30 M at GPR55, CB1 and CB2 respectively) and PPAR agonist (EC50 = 120 nM). Induces satiety through activation of PPAR and is also a ceramidase inhibitor. Also endogenous agonist at the GPR119 receptor.
extended description :
Lipid mediator, anorexic actions; also GPR55 and PPAR agonist
chemical name text :
(9Z)-N-(2-Hydroxyethyl)-9-octadecenamide
formula :
C 20 H 39 NO 2
formula text :
C20H39NO2
cas num :
111-58-0
USD :
129 USD
product details :
Lipid mediator, anorexic actions; also GPR55 and PPAR agonist
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK