product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Etomidate
catalog :
1471/10
quantity :
10 mg (also 50 mg)
price :
197 USD
more info or order :
citations: 3
Reference
Olander E, Madjroh N, Bunch L, Söderhielm P, Jensen A. Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABAA receptors. Biochem Pharmacol. 2018;150:305-319 pubmed publisher
Rodgers F, Zarnowska E, Laha K, Engin E, Zeller A, Keist R, et al. Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABAA Receptors on Nonpyramidal Cells. J Neurosci. 2015;35:9707-16 pubmed publisher
Drasbek K, Hoestgaard Jensen K, Jensen K. Modulation of extrasynaptic THIP conductances by GABAA-receptor modulators in mouse neocortex. J Neurophysiol. 2007;97:2293-300 pubmed
product information
brand :
Tocris
MasterCode :
1471
SKU :
1471/10
product name :
Etomidate
target :
GABA-A Receptor Modulators
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
244.29
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Etomidate is a general anesthetic with GABA modulatory and GABA-mimetic actions; selectively interacts with 2- and 3-subunit containing GABAA receptors. Short acting and potent hypnotic, with low toxicity.
extended description :
GABA-mimetic; selectively interacts with 2- and 3-subunit containing GABAA receptors
chemical name text :
(R)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester
formula :
C 14 H 16 N 2 O 2
formula text :
C14H16N2O2
cas num :
33125-97-2
USD :
197 USD
product details :
GABA-mimetic; selectively interacts with 2- and 3-subunit containing GABAA receptors
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK