TFLLR-NH2 | Tocris Bioscience 1464/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TFLLR-NH2

catalog :

1464/1

quantity :

1 mg

price :

362 USD

more info or order :

Tocris Bioscience product webpage

citations: 11

Reference
Zhang J, Nie D, Williamson K, Rocha J, Hogan M, Wang J. Selectively activated PRP exerts differential effects on tendon stem/progenitor cells and tendon healing. J Tissue Eng. 2019;10:2041731418820034 pubmed publisher
Müller M, Fouyssac M, Taylor C. Effective Glucose Uptake by Human Astrocytes Requires Its Sequestration in the Endoplasmic Reticulum by Glucose-6-Phosphatase-β. Curr Biol. 2018;28:3481-3486.e4 pubmed publisher
Wang H, Ricklin D, Lambris J. Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4. Proc Natl Acad Sci U S A. 2017;114:10948-10953 pubmed publisher
Zhang S, Liu Y, WANG Z, Liu J, Gu Z, Xu Q, et al. PAR1â€‘mediated câ€‘Jun activation promotes heat stressâ€‘induced early stage apoptosis of human umbilical vein endothelial cells. Mol Med Rep. 2017;15:2595-2603 pubmed publisher
Carlsen E, Perrier J. Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord. Front Neural Circuits. 2014;8:60 pubmed publisher
Chen C, Chen Q, Ouyang Q, Sun J, Liu F, Song D, et al. Transient early neurotrophin release and delayed inflammatory cytokine release by microglia in response to PAR-2 stimulation. J Neuroinflammation. 2012;9:142 pubmed publisher
Chen B, Friedman B, Whitney M, Winkle J, Lei I, Olson E, et al. Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci. 2012;32:7622-31 pubmed publisher
Wang F, Smith N, Xu Q, Fujita T, Baba A, Matsuda T, et al. Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+. Sci Signal. 2012;5:ra26 pubmed publisher
Vellani V, Kinsey A, Prandini M, Hechtfischer S, Reeh P, Magherini P, et al. Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones. Mol Pain. 2010;6:61 pubmed publisher
Fujimoto D, Hirono Y, Goi T, Katayama K, Matsukawa S, Yamaguchi A. The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion. BMC Cancer. 2010;10:443 pubmed publisher
Gomez Gonzalo M, Losi G, Chiavegato A, Zonta M, Cammarota M, Brondi M, et al. An excitatory loop with astrocytes contributes to drive neurons to seizure threshold. PLoS Biol. 2010;8:e1000352 pubmed publisher

product information

brand :

Tocris

master code :

1464

SKU :

1464/1

product name :

TFLLR-NH2

description :

PAR1-activating peptide

target :

Protease-Activated Receptor Agonists

category :

Peptides

unit sizes :

1 mg

purity :

95%

observed molecular weight :

647.82

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

TFLLR-NH2 is a peptide derived from the protease-activated receptor-1 (PAR1) that acts as a PAR1 selective agonist (EC50 = 1.9 u M). Stimulates PAR1-mediated plasma extravasation in vivo . . Control Peptide also available.

extended description :

PAR1-activating peptide

formula :

C 31 H 53 N 9 O 6

formula text :

C31H53N9O6

cas num :

197794-83-5

USD :

362 USD

product details :

PAR1-activating peptide

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage