Orexin B (human) | Tocris Bioscience 1456/500U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Orexin B (human)

catalog :

1456/500U

quantity :

500 ug

price :

377 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Guerreiro S, Florence C, Rousseau E, Hamadat S, Hirsch E, Michel P. The sleep-modulating peptide orexin-B protects midbrain dopamine neurons from degeneration, alone or in cooperation with nicotine. Mol Pharmacol. 2015;87:525-32 pubmed publisher
Malherbe P, Borroni E, Gobbi L, Knust H, Nettekoven M, Pinard E, et al. Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor. Br J Pharmacol. 2009;156:1326-41 pubmed publisher

product information

brand :

Tocris

master code :

1456

SKU :

1456/500U

product name :

Orexin B (human)

description :

Endogenous agonist at OX1 and OX2

target :

Orexin Receptor Agonists

category :

Peptides

unit sizes :

500 ug

purity :

95%

species :

Human

observed molecular weight :

2899.36

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Orexin B (human) is an endogenous agonist at orexin receptors (Ki values are 420 and 36 nM for OX1 and OX2 receptors, respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions. Also neuroprotective for dopaminergic neurons in rat midbrain cultures.

extended description :

Endogenous agonist at OX1 and OX2

formula :

C 123 H 212 N 44 O 35 S

formula text :

C123H212N44O35S

cas num :

205640-91-1

USD :

377 USD

product details :

Endogenous agonist at OX1 and OX2

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage