BMS 182874 hydrochloride | Tocris Bioscience 1441/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BMS 182874 hydrochloride

catalog :

1441/10

quantity :

10 mg (also 50 mg)

price :

257 USD

citations: 2

Reference
Yuan X, Eng G, Arkonac D, Chao P, Vunjak Novakovic G. Endothelial cells enhance the migration of bovine meniscus cells. Arthritis Rheumatol. 2015;67:182-92 pubmed publisher
Khan H, Naylor R, Tuladhar B. Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon. Br J Pharmacol. 2006;147:607-11 pubmed

product information

brand :

Tocris

master code :

1441

SKU :

1441/10

product name :

BMS 182874 hydrochloride

description :

Highly selective, orally active non-peptide ETA antagonist

target :

Endothelin ETA Receptor Antagonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

381.88

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BMS 182874 hydrochloride is a potent, selective and competitive non-peptide endothelin ETA receptor antagonist (Ki = 48 nM). Displays 1000-fold selectivity over ETB receptors. Inhibits ET-1-induced pressor response following oral or intravenous administration in vivo . Inhibits ET-1-induced longitudinal muscle contraction in the mouse colon in vitro .

extended description :

Highly selective, orally active non-peptide ETA antagonist

chemical name text :

5-(Dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide hydrochloride

formula :

C 17 H 19 N 3 O 3 S.HCl

formula text :

C17H19N3O3S.HCl

cas num :

1215703-04-0

USD :

244

USD 2023 :

257 USD

product details :

Highly selective, orally active non-peptide ETA antagonist

storage :

Store at RT