DuP 697 | Tocris Bioscience 1430 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DuP 697

catalog :

1430

quantity :

10 mg (also 50 mg)

price :

181 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Gonnermann D, Oberg H, Kellner C, Peipp M, Sebens S, Kabelitz D, et al. Resistance of cyclooxygenase-2 expressing pancreatic ductal adenocarcinoma cells against Î³Î´ T cell cytotoxicity. Oncoimmunology. 2015;4:e988460 pubmed
Alsaqati M, Chan S, Ralevic V. Investigation of the functional expression of purine and pyrimidine receptors in porcine isolated pancreatic arteries. Purinergic Signal. 2014;10:241-9 pubmed publisher
Passafaro D, Sterin Borda L, Reina S, Borda E. Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland. Dent Res J (Isfahan). 2011;8:138-45 pubmed
Choi C, Kim W, Lee H, Jeong C, Kim C, Lee S, et al. Roles of opioid receptor subtype in the spinal antinociception of selective cyclooxygenase 2 inhibitor. Korean J Pain. 2010;23:236-41 pubmed publisher
Wong S, Leung F, Lau C, Au C, Yung L, Yao X, et al. Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging. Circ Res. 2009;104:228-35 pubmed publisher

product information

brand :

Tocris

master code :

1430

SKU :

1430/10

product name :

DuP 697

description :

Cyclooxygenase-2 (COX-2) inhibitor

target :

Cyclooxygenase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

411.3

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective inhibitor of cyclooxygenase-2 (IC50 values are 10 and 800 nM for COX-2 and COX-1 respectively). Inhibits prostaglandin synthesis and is anti-inflammatory in vivo . Orally active.

catalog number base :

1430

product keywords :

Cyclooxygenase-2 COX-2 inhibitors inhibits Cyclooxygenase Oxygenases Oxidases DuP697 Cyclooxygenase 1430,

extended description :

Cyclooxygenase-2 (COX-2) inhibitor

chemical name text :

5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-thiophene

formula :

C 17 H 12 BrFO 2 S 2

formula text :

C17H12BrFO2S2

cas num :

88149-94-4

2020 USD :

175

2021 USD :

181 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage