product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1428/100U
catalog :
1428/100U
quantity :
100 ug
price :
195 USD
more info or order :
citations: 7
Reference
Mouchard A, Boutonnet M, Mazzocco C, Biendon N, Macrez N. ApoE-fragment/Aβ heteromers in the brain of patients with Alzheimer's disease. Sci Rep. 2019;9:3989 pubmed publisher
Chen L, Chai K. Matriptase cleaves the amyloid-beta peptide 1-42 at Arg-5, Lys-16, and Lys-28. BMC Res Notes. 2019;12:5 pubmed publisher
Willén K, Edgar J, Hasegawa T, Tanaka N, Futter C, Gouras G. A? accumulation causes MVB enlargement and is modelled by dominant negative VPS4A. Mol Neurodegener. 2017;12:61 pubmed publisher
Hui C, Zhang Y, Herrup K. Non-Neuronal Cells Are Required to Mediate the Effects of Neuroinflammation: Results from a Neuron-Enriched Culture System. PLoS ONE. 2016;11:e0147134 pubmed publisher
Pourbadie H, Naderi N, Mehranfard N, Janahmadi M, Khodagholi F, Motamedi F. Preventing effect of L-type calcium channel blockade on electrophysiological alterations in dentate gyrus granule cells induced by entorhinal amyloid pathology. PLoS ONE. 2015;10:e0117555 pubmed publisher
Deleglise B, Magnifico S, Duplus E, Vaur P, Soubeyre V, Belle M, et al. β-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network. Acta Neuropathol Commun. 2014;2:145 pubmed publisher
Scuderi C, Valenza M, Stecca C, Esposito G, Carratu M, Steardo L. Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-?. J Neuroinflammation. 2012;9:49 pubmed publisher
product information
master code :
1428
SKU :
1428/100U
product name :
Amyloid beta-peptide (1-42) (human)
unit size :
100 ug
description :
Predominant amyloid -protein fragment
target :
Amyloid beta Peptides
category :
Peptides
purity :
95%
species :
Human
observed molecular weight :
4514.08
gene symbol :
APP
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Amyloid -Peptide (1-42) (human) is a human form of the predominant amyloid -peptide found in the brains of patients with Alzheimer s disease. Downregulates bcl-2 and increases the levels of bax. Neurotoxic. . Control Peptide also available.
top caption :
Predominant amyloid -protein fragment
extended description :
Predominant amyloid -protein fragment
formula :
C203H311N55O60S
formula text :
C203H311N55O60S
cas num :
107761-42-2
USD :
195 USD
product details :
Predominant amyloid -protein fragment
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK