product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1418/100
catalog :
1418/100
quantity :
100 mg
price :
150 USD
more info or order :
citations: 7
Reference
Meftahi G, Ghotbedin Z, Eslamizade M, Hosseinmardi N, Janahmadi M. Suppressive Effects of Resveratrol Treatment on The Intrinsic Evoked Excitability of CA1 Pyramidal Neurons. Cell J. 2015;17:532-9 pubmed
Chen H, Guo S, Li Z, Lu Y, Jiang D, Zhang R, et al. A critical role for interferon regulatory factor 9 in cerebral ischemic stroke. J Neurosci. 2014;34:11897-912 pubmed publisher
Rojas F, Cortes N, Abarzúa S, Dyrda A, van Zundert B. Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress. Front Cell Neurosci. 2014;8:24 pubmed publisher
Jiang Y, Zsombok A. Regulation of neurons in the dorsal motor nucleus of the vagus by SIRT1. Front Neurosci. 2014;7:270 pubmed publisher
Wang H, Wu C, Cheng T, Kuo C, Tsai Y, Chiang S, et al. Active Constituents from Liriope platyphylla Root against Cancer Growth In Vitro. Evid Based Complement Alternat Med. 2013;2013:857929 pubmed publisher
Pacholec M, Bleasdale J, Chrunyk B, Cunningham D, Flynn D, Garofalo R, et al. SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1. J Biol Chem. 2010;285:8340-51 pubmed publisher
Ohshiro K, Rayala S, Kondo S, Gaur A, Vadlamudi R, El Naggar A, et al. Identifying the estrogen receptor coactivator PELP1 in autophagosomes. Cancer Res. 2007;67:8164-71 pubmed
product information
master code :
1418
SKU :
1418/100
product name :
Resveratrol
unit size :
100 mg
description :
Cyclooxygenase inhibitor
target :
Cyclooxygenase Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
228.25
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Resveratrol is a phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC50 = 23 u M) and displays mixed agonist/antagonist actions at ER and ER estrogen receptors. Converted into the anticancer agent piceatannol (Cat. No. 1554) by cytochrome P450 1B1. Activates autophagy. Also activates TRPA1 in prostate cancer-associated fibroblasts. Also SIRT1 activator.
top caption :
Cyclooxygenase inhibitor
extended description :
Cyclooxygenase inhibitor
chemical name text :
5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol
formula :
C14H12O3
formula text :
C14H12O3
cas num :
501-36-0
USD :
150 USD
product details :
Cyclooxygenase inhibitor
storage :
Desiccate at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK