NAS-181 | Tocris Bioscience 1413 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NAS-181

catalog :

1413

quantity :

10 mg (also 50 mg)

price :

259 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Xiao Y, RICHTER J, Hurley J. Release of glutamate and CGRP from trigeminal ganglion neurons: Role of calcium channels and 5-HT1 receptor signaling. Mol Pain. 2008;4:12 pubmed publisher

product information

brand :

Tocris

master code :

1413

SKU :

1413/10

product name :

NAS-181

description :

Selective r5-HT1B antagonist; active in vivo

target :

5-HT1B Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

538.63

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, selective antagonist at the rat 5-HT1B receptor (Ki = 47 nM). Increases synthesis and metabolism of 5-HT in the brain following systemic administration and improves passive avoidance retention performance in vivo . Increases subthalamic nucleus-triggered complex EPSCs and burst firing in SNr GABA neurons

catalog number base :

1413

product keywords :

Selective r5-HT1B antagonist Active vivo Serotonin Receptors 5-HT1B Receptors 1413,

extended description :

Selective r5-HT1B antagonist; active in vivo

chemical name text :

(2R)-2-[[[3-(4-Morpholinylmethyl)-2H-1-benzopyran-8-yl]oxy]methyl]morpholine dimethanesulfonate

formula :

C 19 H 26 N 2 O 4 .2CH 3 SO 3 H

formula text :

C19H26N2O4.2CH3SO3H

cas num :

1217474-40-2

2020 USD :

249

2021 USD :

259 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage