Kenpaullone | Tocris Bioscience 1398 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Kenpaullone

catalog :

1398

quantity :

10 mg

price :

193 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Du Z, Chen H, Liu H, Lu J, Qian K, Huang C, et al. Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells. Nat Commun. 2015;6:6626 pubmed publisher
Goonesekere N, Wang X, Ludwig L, Guda C. A meta analysis of pancreatic microarray datasets yields new targets as cancer genes and biomarkers. PLoS ONE. 2014;9:e93046 pubmed publisher

product information

brand :

Tocris

master code :

1398

SKU :

1398/10

product name :

Kenpaullone

description :

GSK-3 inhibitor; also inhibits cdks

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

327.18

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GSK-3beta inhibitor (IC50 = 0.23 M). Also inhibits cyclin dependent kinases (cdks) in the sub micromolar range (reported IC50 values are 0.4, 0.68-7 and 0.85 M for cdk1, cdk2 and cdk5, respectively). Generates induced pluripotent stem cells (iPSCs) from somatic cells when used in combination with reprogramming factors; can replace Klf4.

catalog number base :

1398

product keywords :

GSK-3 GSK-3beta inhibitors inhibits cdks Potent cyclin-dependent kinase GSK Glycogen Synthase Kinase 3 beta Kinases Cdk Cyclin-Dependent Protein Carbohydrate Metabolism CDK1/cyclin B CDK2/cyclin A E CDK5/cyclin/p35 stem cells Cyclin-dependent Kinase Glycogen Synthase Kinase 3 Glycogen Synthase Kinase Stem Cell Reprogramming 1398,

extended description :

GSK-3 inhibitor; also inhibits cdks

chemical name text :

9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one

formula :

C 16 H 11 BrN 2 O

formula text :

C16H11BrN2O

cas num :

142273-20-9

2020 USD :

187

2021 USD :

193 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage