product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1396/10
catalog :
1396/10
quantity :
10 mg (also 50 mg)
price :
210 USD
more info or order :
citations: 6
Reference
Xie S, García Prat L, Voisin V, Ferrari R, Gan O, Wagenblast E, et al. Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal. Cell Stem Cell. 2019;25:639-653.e7 pubmed publisher
Catanese A, Olde Heuvel F, Mulaw M, Demestre M, Higelin J, Barbi G, et al. Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation. Autophagy. 2019;:1-19 pubmed publisher
Lancaster G, Langley K, Berglund N, Kammoun H, Reibe S, Estevez E, et al. Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism. Cell Metab. 2018;27:1096-1110.e5 pubmed publisher
Jung W, Liu C, Yu Y, Chang Y, Lien W, Chao H, et al. Lipophagy prevents activity-dependent neurodegeneration due to dihydroceramide accumulation in vivo. EMBO Rep. 2017;18:1150-1165 pubmed publisher
Seidensaal K, Nollert A, Feige A, Muller M, Fleming T, Gunkel N, et al. Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma. Mol Cancer. 2015;14:204 pubmed publisher
Johansson H, Sanchez B, Mundt F, Forshed J, Kovács A, Panizza E, et al. Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer. Nat Commun. 2013;4:2175 pubmed publisher
product information
master code :
1396
SKU :
1396/10
product name :
Fenretinide
unit size :
10 mg (also 50 mg)
description :
Synthetic retinoid; antiproliferative and antioxidant
target :
Additional Retinoic Acid Receptor Compounds
category :
Small Molecules
purity :
98%
observed molecular weight :
391.55
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Fenretinide is a synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo . Apoptotic effects appear to be mediated by a mechanism distinct from that of classical retinoids.
top caption :
Synthetic retinoid; antiproliferative and antioxidant
extended description :
Synthetic retinoid; antiproliferative and antioxidant
chemical name text :
N-(4-Hydroxyphenyl)retinamide
formula :
C26H33NO2
formula text :
C26H33NO2
cas num :
65646-68-6
USD :
210 USD
product details :
Synthetic retinoid; antiproliferative and antioxidant
alt names :
4-HPR
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK