PMPA (NAALADase inhibitor) | Tocris Bioscience 1380 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PMPA (NAALADase inhibitor)

catalog :

1380

quantity :

10 mg (also 50 mg)

price :

162 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Schottelius M, Wurzer A, Wissmiller K, Beck R, Koch M, Gorpas D, et al. Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer. J Nucl Med. 2019;60:71-78 pubmed publisher

product information

brand :

Tocris

master code :

1380

SKU :

1380/10

product name :

PMPA (NAALADase inhibitor)

description :

GCP II inhibitor

target :

Carboxypeptidase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

observed molecular weight :

226.12

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Highly potent and selective inhibitor of glutamate carboxypeptidase 2 (GCP II/N-acetylated -linked dipeptidase/NAALADase) with a Ki value of 275 pM. Neuroprotective; protects against glutamate-mediated motor neuron degeneration and reduces volume of injury following middle cerebral artery occlusion (MCAO).

catalog number base :

1380

product keywords :

potent selective NAALADase GCP II inhibitors inhibits Carboxypeptidase NAAG Peptidase Proteinases Proteases AstraZeneca Miscellaneous Glutamate Carboxypeptidase 1380,

extended description :

GCP II inhibitor

chemical name text :

2-(Phosphonomethyl)pentane-1,5-dioic acid

formula :

C 6 H 11 O 7 P

formula text :

C6H11O7P

cas num :

173039-10-6

2020 USD :

155

2021 USD :

162 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage