ZM 39923 hydrochloride | Tocris Bioscience 1367 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ZM 39923 hydrochloride

catalog :

1367

quantity :

10 mg (also 50 mg)

price :

195 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Rogers S, Gahring L. Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways. PLoS ONE. 2015;10:e0143319 pubmed publisher
Vidro Kotchan E, Yendluri B, Le Thai T, Tsin A. NBHA reduces acrolein-induced changes in ARPE-19 cells: possible involvement of TGF?. Curr Eye Res. 2011;36:370-8 pubmed publisher
Schaertl S, Prime M, Wityak J, Dominguez C, Munoz Sanjuan I, Pacifici R, et al. A profiling platform for the characterization of transglutaminase 2 (TG2) inhibitors. J Biomol Screen. 2010;15:478-87 pubmed publisher

product information

brand :

Tocris

master code :

1367

SKU :

1367/10

product name :

ZM 39923 hydrochloride

description :

Potent, selective JAK3 inhibitor

target :

JAK Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

367.92

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3). pIC50 values are 7.1, 5.6, 4.4, and 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively. Breaks down in neutral buffer (t = 36 mins, pH 7.43, 25 C) to form ZM 449829 (Cat. No. 1366).

catalog number base :

1367

product keywords :

Potent selective JAK3 inhibitors inhibits Janus Activated Kinase JAK Kinases ZM39923 hydrochloride HCl AstraZeneca 58753-54-1 JAK Kinase 1367,

extended description :

Potent, selective JAK3 inhibitor

chemical name text :

3-benzylisopropylamino-1-naphthalen-2-yl-propan-1-one hydrochloride

formula :

C 23 H 25 NO.HCl

formula text :

C23H25NO.HCl

cas num :

1021868-92-7

2020 USD :

189

2021 USD :

195 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage