P1075 | Tocris Bioscience 1355 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

P1075

catalog :

1355

quantity :

10 mg (also 50 mg)

price :

210 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Cao C, Lee Kwon W, Silldorff E, Pallone T. KATP channel conductance of descending vasa recta pericytes. Am J Physiol Renal Physiol. 2005;289:F1235-45 pubmed
Baczkó I, Jones L, McGuigan C, Manning Fox J, Gandhi M, Giles W, et al. Plasma membrane KATP channel-mediated cardioprotection involves posthypoxic reductions in calcium overload and contractile dysfunction: mechanistic insights into cardioplegia. FASEB J. 2005;19:980-2 pubmed

product information

brand :

Tocris

master code :

1355

SKU :

1355/10

product name :

P1075

description :

Potent Kir6 (KATP) channel opener

target :

Inward Rectifier Potassium Channel Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

231.3

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent Kir6 (KATP) channel opener (EC50 for relaxation of rat aorta = 7.5 nM). Binds to SUR2A and SUR2B with high affinity (Kd values are 17 and 3 nM respectively).

catalog number base :

1355

product keywords :

Potent KATP channel openers Potassium KIR Channels Inward Rectifier K+ Kir6 Inward rectifier Potassium Channels 1355,

extended description :

Potent Kir6 (KATP) channel opener

chemical name text :

N-cyano-N -(1,1-dimethylpropyl)-N -3-pyridylguanidine

formula :

C 12 H 17 N 5

formula text :

C12H17N5

cas num :

60559-98-0

2020 USD :

203

2021 USD :

210 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage