product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1349/10
catalog :
1349/10
quantity :
10 mg (also 50 mg)
price :
272 USD
more info or order :
citations: 2
Reference
Boomkamp S, McGrath M, Houslay M, Barnett S. Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. Br J Pharmacol. 2014;171:2385-98 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
product information
master code :
1349
SKU :
1349/10
product name :
(R)-(-)-Rolipram
unit size :
10 mg (also 50 mg)
description :
PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905)
target :
Phosphodiesterase Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
275.35
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
( R )-(-)-Rolipram is a more active enantiomer of the PDE4 inhibitor rolipram; 2-10-fold more potent than the S-(+) enantiomer. . Racemate and S-enantiomer also available.
top caption :
PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905)
extended description :
PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905)
chemical name text :
(4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
formula :
C16H21NO3
formula text :
C16H21NO3
cas num :
85416-75-7
USD :
272 USD
product details :
PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905)
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK