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company name :
Tocris Bioscience
product type :
chemical
product name :
cAMPS-Rp, triethylammonium salt
catalog :
1337
quantity :
1 mg
price :
172 USD
more info or order :
citations: 13
Reference
Katrancha S, Shaw J, Zhao A, Myers S, Cocco A, Jeng A, et al. Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits. Cell Rep. 2019;26:2805-2817.e9 pubmed publisher
Xu H, Rajsombath M, Weikop P, Selkoe D. Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β. EMBO Mol Med. 2018;10: pubmed publisher
Inda C, Bonfiglio J, Dos Santos Claro P, Senin S, Armando N, Deussing J, et al. cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells. Sci Rep. 2017;7:1944 pubmed publisher
Tuesta L, Chen Z, Duncan A, Fowler C, Ishikawa M, Lee B, et al. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nat Neurosci. 2017;20:708-716 pubmed publisher
Inda C, Dos Santos Claro P, Bonfiglio J, Senin S, Maccarrone G, Turck C, et al. Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling. J Cell Biol. 2016;214:181-95 pubmed publisher
Tozzi A, de Iure A, Tantucci M, Durante V, Quiroga Varela A, Giampà C, et al. Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system. Front Cell Neurosci. 2015;9:192 pubmed publisher
Schwer C, Lehane C, Guelzow T, Zenker S, Strosing K, Spassov S, et al. Thiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell death. PLoS ONE. 2013;8:e77258 pubmed publisher
Cho J, Zushida K, Shumyatsky G, Carlezon W, Meloni E, Bolshakov V. Pituitary adenylate cyclase-activating polypeptide induces postsynaptically expressed potentiation in the intra-amygdala circuit. J Neurosci. 2012;32:14165-77 pubmed publisher
Crawford D, Jiang X, Taylor A, Mennerick S. Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro. J Neurosci. 2012;32:13100-10 pubmed
del Puerto A, Díaz Hernández J, Tapia M, Gomez Villafuertes R, Benitez M, Zhang J, et al. Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation. J Cell Sci. 2012;125:176-88 pubmed publisher
Xu T, Ma Q, Spealman R, Yao W. Amphetamine modulation of long-term potentiation in the prefrontal cortex: dose dependency, monoaminergic contributions, and paradoxical rescue in hyperdopaminergic mutant. J Neurochem. 2010;115:1643-54 pubmed publisher
Silberman Y, Ariwodola O, Chappell A, Yorgason J, Weiner J. Lateral paracapsular GABAergic synapses in the basolateral amygdala contribute to the anxiolytic effects of beta 3 adrenoceptor activation. Neuropsychopharmacology. 2010;35:1886-96 pubmed publisher
Sutton G, Duos B, Patterson L, Berthoud H. Melanocortinergic modulation of cholecystokinin-induced suppression of feeding through extracellular signal-regulated kinase signaling in rat solitary nucleus. Endocrinology. 2005;146:3739-47 pubmed
product information
brand :
Tocris
master code :
1337
SKU :
1337/1
product name :
cAMPS-Rp, triethylammonium salt
description :
cAMP antagonist
target :
cAMP Compounds
category :
Small Molecules
unit size :
1 mg
purity :
98%
observed molecular weight :
446.46
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cell-permeable cAMP analog; acts as a competitive antagonist of cAMP-induced activation of PKA (IC50 = 11 - 16 u M) by interacting with cAMP binding sites on the regulatory subunits. Resistant to hydrolysis by phosphodiesterases.
catalog number base :
1337
product keywords :
cAMP analog Cyclic adenosines Monophosphate Rp-camps cAMP Protein Kinase A 1337,
extended description :
cAMP antagonist
chemical name text :
(R)-Adenosine, cyclic 3 ,5 -(hydrogenphosphorothioate) triethylammonium
formula :
C 10 H 12 N 5 O 5 PS.C 6 H 15 N
formula text :
C10H12N5O5PS.C6H15N
cas num :
151837-09-1
2020 USD :
163
2021 USD :
172 USD
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK