1337/1 | Tocris Bioscience 1337/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1337/1

catalog :

1337/1

quantity :

1 mg

price :

221 USD

more info or order :

Tocris Bioscience product webpage

citations: 17

Reference
Mitlöhner J, Kaushik R, Niekisch H, Blondiaux A, Gee C, Happel M, et al. Dopamine Receptor Activation Modulates the Integrity of the Perisynaptic Extracellular Matrix at Excitatory Synapses. Cells. 2020;9: pubmed publisher
Katrancha S, Shaw J, Zhao A, Myers S, Cocco A, Jeng A, et al. Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits. Cell Rep. 2019;26:2805-2817.e9 pubmed publisher
Xu H, Rajsombath M, Weikop P, Selkoe D. Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β. EMBO Mol Med. 2018;10: pubmed publisher
Cao W, Xu Y, Luo D, Saeed M, Sun C. Hoxa5 Promotes Adipose Differentiation via Increasing DNA Methylation Level and Inhibiting PKA/HSL Signal Pathway in Mice. Cell Physiol Biochem. 2018;45:1023-1033 pubmed publisher
Inda C, Bonfiglio J, Dos Santos Claro P, Senin S, Armando N, Deussing J, et al. cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells. Sci Rep. 2017;7:1944 pubmed publisher
Tuesta L, Chen Z, Duncan A, Fowler C, Ishikawa M, Lee B, et al. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nat Neurosci. 2017;20:708-716 pubmed publisher
Inda C, Dos Santos Claro P, Bonfiglio J, Senin S, Maccarrone G, Turck C, et al. Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling. J Cell Biol. 2016;214:181-95 pubmed publisher
Schlam D, Canton J, Carreño M, Kopinski H, Freeman S, Grinstein S, et al. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. MBio. 2016;7:e02242 pubmed publisher
Tozzi A, de Iure A, Tantucci M, Durante V, Quiroga Varela A, GiampÃ C, et al. Endogenous 17Î²-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system. Front Cell Neurosci. 2015;9:192 pubmed publisher
Belgacem Y, Borodinsky L. Inversion of Sonic hedgehog action on its canonical pathway by electrical activity. Proc Natl Acad Sci U S A. 2015;112:4140-5 pubmed publisher
Schwer C, Lehane C, Guelzow T, Zenker S, Strosing K, Spassov S, et al. Thiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell death. PLoS ONE. 2013;8:e77258 pubmed publisher
Cho J, Zushida K, Shumyatsky G, Carlezon W, Meloni E, Bolshakov V. Pituitary adenylate cyclase-activating polypeptide induces postsynaptically expressed potentiation in the intra-amygdala circuit. J Neurosci. 2012;32:14165-77 pubmed publisher
Crawford D, Jiang X, Taylor A, Mennerick S. Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro. J Neurosci. 2012;32:13100-10 pubmed
del Puerto A, Díaz Hernández J, Tapia M, Gomez Villafuertes R, Benitez M, Zhang J, et al. Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation. J Cell Sci. 2012;125:176-88 pubmed publisher
Xu T, Ma Q, Spealman R, Yao W. Amphetamine modulation of long-term potentiation in the prefrontal cortex: dose dependency, monoaminergic contributions, and paradoxical rescue in hyperdopaminergic mutant. J Neurochem. 2010;115:1643-54 pubmed publisher
Silberman Y, Ariwodola O, Chappell A, Yorgason J, Weiner J. Lateral paracapsular GABAergic synapses in the basolateral amygdala contribute to the anxiolytic effects of beta 3 adrenoceptor activation. Neuropsychopharmacology. 2010;35:1886-96 pubmed publisher
Sutton G, Duos B, Patterson L, Berthoud H. Melanocortinergic modulation of cholecystokinin-induced suppression of feeding through extracellular signal-regulated kinase signaling in rat solitary nucleus. Endocrinology. 2005;146:3739-47 pubmed

product information

master code :

1337

SKU :

1337/1

product name :

cAMPS-Rp, triethylammonium salt

unit size :

1 mg

description :

cAMP antagonist

target :

cAMP Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

446.46

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

cAMPS-Rp, triethylammonium salt is a cell-permeable cAMP analog; acts as a competitive antagonist of cAMP-induced activation of PKA (IC50 = 11 - 16 u M) by interacting with cAMP binding sites on the regulatory subunits. Resistant to hydrolysis by phosphodiesterases.

top caption :

cAMP antagonist

extended description :

cAMP antagonist

chemical name text :

(R)-Adenosine, cyclic 3 ,5 -(hydrogenphosphorothioate) triethylammonium

formula :

C10H12N5O5PS.C6H15N

formula text :

C10H12N5O5PS.C6H15N

cas num :

151837-09-1

USD :

221 USD

product details :

cAMP antagonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage