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company name :
Tocris Bioscience
product type :
chemical
product name :
Bafilomycin A1
catalog :
1334/10U
quantity :
10 ug
price :
146 USD
more info or order :
citations: 51
Reference
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product information
brand :
Tocris
SKU :
1334/10U
product name :
Bafilomycin A1
unit sizes :
10 ug
description :
H+-ATPase (vacuolar) inhibitor
target :
H+-ATPase Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
622.84
details of functionality :
Highly potent, selective inhibitor of vacuolar H+-ATPases (IC50 = 0.6 - 1.5 nM in bovine chromaffin granules). Selective for v-ATPase over other ATP hydrolyzing enzymes such as F-ATPases and the H+/K+-ATPase (P-ATPase). Thought to inhibit autophagy either by blocking autophagosome-lysosome fusion (in H4IIE cells), or by blocking lysosomal degradation.
catalog number base :
1334
extended description :
H+-ATPase (vacuolar) inhibitor
chemical name text :
(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one
formula :
C 35 H 58 O 9
formula text :
C35H58O9
cas num :
88899-55-2
USD :
146 USD
product details :
H+-ATPase (vacuolar) inhibitor
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK