Bafilomycin A1 | Tocris Bioscience 1334/10 product information

product summary

request information :

company name :

Tocris Bioscience

product type :

chemical

product name :

Bafilomycin A1

catalog :

1334/10

quantity :

10µg

price :

125 USD

more info or order :

Tocris Bioscience product webpage

product information

CHEMISTRY :

O[C@H]([C@H](C)/C=C(C)/C=C1OC)[C@@H](C)C/C(C)=C/C=C [C@H](OC)C([C@@H](C)[C@H]([C@@H]([C@@]2(O)C[C@@H](O)[C@H](C)[C@@H]([C@H](C)C)O2)C)O)OC/1=O

Cat Number :

1334/10

Product Name :

Bafilomycin A1

Cas Number :

[88899-55-2]

Unit Size :

10µg

Size :

Unit :

µg

USD :

125 USD

Primary Category :

Enzymes

Secondary Category :

ATPases/GTPases

Tertiary Category :

ATPase

Primary Action :

H+-ATPase (vacuolar) inhibitor

Biological Description :

Highly potent, selective inhibitor of vacuolar H+-ATPases (IC50 = 0.6 - 1.5 nM in bovine chromaffin granules). Selective for v-ATPase over other ATP hydrolyzing enzymes such as F-ATPases and the H+/K+-ATPase (P-ATPase). Thought to inhibit autophagy either by blocking autophagosome-lysosome fusion (in H4IIE cells), or by blocking lysosomal degradation.

Formula :

C35H58O9

Molwt :

622.84

more info or order :

Tocris Bioscience product webpage